Evidence map›Paper›PMID 42902909›Full record

ArticleChemistry & biodiversity2026

Integrative Assessment of Teucrium Extracts: Phytochemical Profile, Nutritional-Mineral Composition, Biological Activities, and Toxicological Assessment In Vitro and In Vivo.

Kenan Preljević, Ivana Pašić, Milorad Vlaović, Svetlana Perović, Slađana Krivokapić, Tatjana Stanojković, Ana Todorović, Katarina Bobić, Dejan Jančić, Milka Jadranin and 4 more

Abstract read
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In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kenan PreljevićDepartment of Biology, Faculty of Sciences and Mathematics, University of Montenegro, Podgorica, Montenegro.ORCID https://orcid.org/0009-0008-5976-0967
Ivana PašićInstitute for Oncology and Radiology of Serbia, Belgrade, Serbia.ORCID https://orcid.org/0000-0002-2404-2841
Milorad VlaovićDepartment of Biology, Faculty of Sciences and Mathematics, University of Montenegro, Podgorica, Montenegro.ORCID https://orcid.org/0009-0004-6616-0194
Svetlana PerovićDepartment of Biology, Faculty of Sciences and Mathematics, University of Montenegro, Podgorica, Montenegro.
Slađana KrivokapićDepartment of Biology, Faculty of Sciences and Mathematics, University of Montenegro, Podgorica, Montenegro.
Tatjana StanojkovićInstitute for Oncology and Radiology of Serbia, Belgrade, Serbia.
Ana TodorovićDepartment of Molecular Biology and Endocrinology, VINČA Institute of Nuclear Sciences-National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia.
Katarina BobićDepartment of Molecular Biology and Endocrinology, VINČA Institute of Nuclear Sciences-National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia.
Dejan JančićFaculty of Food Technology, Food Safety and Ecology - University of Donja Gorica, Podgorica, Montenegro.
Milka JadraninDepartment of Chemistry, University of Belgrade-Institute of Chemistry, Technology, and Metallurgy, Belgrade, Serbia.ORCID https://orcid.org/0000-0002-4235-3504
Gorica VukovićField Test D.O.O, Belgrade, Serbia.
Andrej PerovićDepartment of Biology, Faculty of Sciences and Mathematics, University of Montenegro, Podgorica, Montenegro.
Biljana Damjanović-VratnicaFaculty of Technology, University of Montenegro, Podgorica, Montenegro.
Ivana Z MatićInstitute for Oncology and Radiology of Serbia, Belgrade, Serbia.ORCID https://orcid.org/0000-0001-7364-2619

Funding

Ministry of Education, Science and Innovation of MontenegroMinistry of Science, Technological Development, and Innovation of the Republic of Serbia 451-03-33/2026-03/200043,451-03-33/2026-03/200017,451-03-33/2026-03/200026
6 · The paper itself

Abstract

The qualitative and quantitative analysis of the Teucrium capitatum and Teucrium montanum extracts, assessment of the antioxidant, antimicrobial, and anticancer effects, and in vivo evaluation of acute oral toxicity, were conducted. T. capitatum extract contained higher amounts of flavonoids and phenolic acids than T. montanum extract. Considering the mineral composition, higher concentrations of elements were found in the T. montanum extract compared to the T. capitatum extract. The extract obtained from T. montanum exerted stronger antioxidant and antimicrobial activities than the T. capitatum extract. The ethanolic extract of T. capitatum showed the strongest cytotoxic effects against HeLa, A549, and A375 cancer cell lines, while the T. montanum extract demonstrated weaker cytotoxicity. The extracts triggered apoptosis in HeLa cells. Aqueous extracts did not cause systemic toxicity in Wistar rats. The pharmacological potential of Teucrium extracts rich in phytochemicals and showing antioxidant, cytoprotective, antimicrobial, and cytotoxic effects should be explored in further studies.

Indexed as

Anti-Bacterial AgentsAntineoplastic Agents, PhytogenicAntioxidantsMineralsPhytochemicalsPlant ExtractsTeucriumAnimalsApoptosisBiphenyl CompoundsCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorHumansMaleMicrobial Sensitivity TestsAnti-Bacterial AgentsAntineoplastic Agents, PhytogenicAntioxidantsBiphenyl CompoundsMineralsPhytochemicalsPlant Extractsteucrium extractantioxidantscancer researchphytochemicalsTeucrium capitatumTeucrium montanumtoxicityWistar rats

Identifiers

PMID42902909
PMCPMC13684054

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.