Evidence map›Paper›PMID 42902722›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2026

[Preliminary evaluation of the efficacy and safety of telitacicept in children with IgA nephropathy].

Jie Chen, Xiao-Xia Yu, Xiao-Song Shi, Bing Chen, Shen Wu, Ri-Rong Zhong

Abstract readEnglish Abstract
In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jie ChenDepartment of Pediatrics, Fujian Provincial Hospital Affiliated to Fuzhou University/Provincial Clinical Medical College of Fujian Medical University, Fuzhou 350001, China.
Xiao-Xia YuDepartment of Pediatrics, Fujian Provincial Hospital Affiliated to Fuzhou University/Provincial Clinical Medical College of Fujian Medical University, Fuzhou 350001, China.
Xiao-Song ShiDepartment of Pediatrics, Fujian Provincial Hospital Affiliated to Fuzhou University/Provincial Clinical Medical College of Fujian Medical University, Fuzhou 350001, China.
Bing ChenDepartment of Pediatrics, Fujian Provincial Hospital Affiliated to Fuzhou University/Provincial Clinical Medical College of Fujian Medical University, Fuzhou 350001, China.
Shen WuDepartment of Pediatrics, Fujian Provincial Hospital Affiliated to Fuzhou University/Provincial Clinical Medical College of Fujian Medical University, Fuzhou 350001, China.
Ri-Rong ZhongDepartment of Pediatrics, Fujian Provincial Hospital Affiliated to Fuzhou University/Provincial Clinical Medical College of Fujian Medical University, Fuzhou 350001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo preliminarily assess the efficacy and safety of telitacicept in pediatric IgA nephropathy (IgAN).

methodsClinical data of 11 children with IgAN who received telitacicept in the Department of Pediatrics, Provincial Hospital Affiliated to Fuzhou University, from January 2024 to October 2025 were retrospectively collected. Parameters compared before and after treatment included 24-hour urinary protein, serum albumin, immunoglobulins (IgG, IgA, IgM), peripheral blood CD19

resultsAt 4, 12, 24, 36, and 48 weeks after treatment, 24-hour urinary protein was significantly lower than baseline (all

conclusionsTelitacicept can effectively reduce proteinuria in children with IgAN and demonstrates an overall favorable safety profile.

Indexed as

Glomerulonephritis, IGAAdolescentChildChild, PreschoolFemaleGlomerular Filtration RateHumansImmunoglobulin AMaleRecombinant Fusion ProteinsRetrospective StudiesImmunoglobulin ARecombinant Fusion ProteinstelitaciceptChildEfficacyIgA nephropathySafetyTelitacicept

Identifiers

PMID42902722
PMCPMC13684094

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.