Evidence map›Paper›PMID 42902420›Full record

SynthesisBMC nutrition2026

Association between adherence to the Mediterranean diet and risk of sarcopenia: a systematic review and dose-response meta-analysis of observational studies.

Chenping Xi, Jiaqi Wang, Xiaolin Liu, Caijuan Si, Xiaohua Ke, Huiting Zhou

Abstract readSystematic Review
In one paragraph

Synthesis in BMC nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chenping Xi *Department of Rehabilitation Medicine, Zhejiang Hospital, Lingyin Road Number 12, Xihu District, Hangzhou, Zhejiang, 310013, The People's Republic of China.
Jiaqi Wang *Department of Rehabilitation Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, 200434, The People's Republic of China.
Xiaolin LiuDepartment of Rehabilitation Medicine, Zhejiang Hospital, Lingyin Road Number 12, Xihu District, Hangzhou, Zhejiang, 310013, The People's Republic of China.
Caijuan SiDepartment of Nutrition, Zhejiang Hospital, Lingyin Road Number 12, Xihu District, Hangzhou, Zhejiang, 310013, The People's Republic of China.
Xiaohua KeDepartment of Rehabilitation Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, 200434, The People's Republic of China. kxh22@tongji.edu.cn.
Huiting ZhouDepartment of Rehabilitation Medicine, Zhejiang Hospital, Lingyin Road Number 12, Xihu District, Hangzhou, Zhejiang, 310013, The People's Republic of China. 13666602283@139.com.

Funding

Medical and Health research fund project of Zhejiang Province 2021KY435Science and Technology Project for Disease Prevention and Control of Zhejiang Province 2026JKY123the Research Launch Project of The Fourth People's Hospital Affiliated to Tongji University sykyqd08101
6 · The paper itself

Abstract

backgroundEpidemiological studies have investigated the potential association between adherence to the Mediterranean diet and risk of sarcopenia, with inconsistent results.

objectiveThe current systematic review and meta-analysis was conducted to synthesize available evidence regarding the association between adherence to the Mediterranean diet and risk of sarcopenia.

methodsThis review followed PRISMA guidelines and was registered in PROSPERO (CRD420251145903). A comprehensive literature search was conducted in four electronic databases, including ISI Web of Science, PubMed, Embase, China National Knowledge Infrastructure (CNKI) from database inception to July 2025. Random-effects model was applied to calculate the pooled odd ratios (ORs) and 95% confidence intervals (CIs) for the highest versus lowest categories of Mediterranean diet score in relation to sarcopenia risk. The Cochran's Q test and I-squared (I

resultsSeven observational studies (3 cohort and 4 cross-sectional studies) with 9,709 participants were included. The results showed that high adherence to the Mediterranean diet was significantly associated with a reduced risk of sarcopenia (OR = 0.81; 95%CI:0.71-0.92, P = 0.002), with substantial heterogeneity (I

conclusionsOur study suggested that high adherence to the Mediterranean diet was associated with a 19% reduced risk of sarcopenia. Further large prospective studies and randomized controlled trials are needed to affirm these findings.

trial registrationPROSPERO CRD420251145903.

Indexed as

Dose-response analysisEpidemiologyMediterranean dietMeta-analysisSarcopenia

Identifiers

PMID42902420
PMCPMC13685160

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.