Evidence map›Paper›PMID 42902354›Full record

ArticleJournal of medical case reports2026

Thyroid nodule treated by herbal food composite formulation: a case report.

Yi You, Hui Li

Abstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yi YouMOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, 200438, China.
Hui LiMOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, 200438, China. LHCA@Fudan.edu.cn.ORCID http://orcid.org/0000-0002-7642-215X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThyroid nodules are a prevalent endocrine disorder with a global prevalence estimated to range from 5% to 67%. Conventional treatments, including surveillance, levothyroxine suppression therapy, and surgical resection, are often limited by side effects, invasiveness, and variable efficacy. To date, documented instances of spontaneous regression are exceedingly rare. CASE PRESENTATION: In this case report, we present a 48-year-old Chinese Asian woman with bilateral thyroid nodules who experienced significant nodule regression after a 3.5-month intervention with herbal food composite formulation. The formula, comprising Aronia melanocarpa, Daucus carota, Apium graveolens, Citrus paradisi, and Litchi chinensis, was consumed as juice every other day post-lunch. The patient's ultrasound examination showed multiple mixed echogenic nodules in both thyroid lobes, with the largest nodule measuring 20.7 × 10.4 mm. After treatment, the nodules significantly decreased in size, and a lymph node in the left neck disappeared.

conclusionsThis case raises the possibility that the herbal food composite formulation may have potential value to be explored as an auxiliary therapy for thyroid nodules, warranting further investigation in larger patient populations.

Indexed as

Thyroid NoduleFemaleHumansMiddle AgedTreatment OutcomeUltrasonographyAuxiliary treatmentCase reportInflammationRegressionThyroid nodule

Identifiers

PMID42902354
PMCPMC13685094

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.