Evidence map›Paper›PMID 42902130›Full record

ArticleBMC plant biology2026

FabHLH130-FaSPS1/FaINV positively contributes to the sugar accumulation in strawberry fruits.

Yanhong Song, Lifeng Liu, Luyi Zhao, Wenting Zheng, Pan Song, Xia Zhao, Gang Li, Houcheng Zhou

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In one paragraph

Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yanhong Song *National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Gangwan Road No.28, Guancheng Region, Zhengzhou, 450009, China.
Lifeng Liu *National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Gangwan Road No.28, Guancheng Region, Zhengzhou, 450009, China.
Luyi ZhaoNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Gangwan Road No.28, Guancheng Region, Zhengzhou, 450009, China.
Wenting ZhengNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Gangwan Road No.28, Guancheng Region, Zhengzhou, 450009, China.
Pan SongNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Gangwan Road No.28, Guancheng Region, Zhengzhou, 450009, China.
Xia ZhaoNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Gangwan Road No.28, Guancheng Region, Zhengzhou, 450009, China.
Gang LiNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Gangwan Road No.28, Guancheng Region, Zhengzhou, 450009, China.
Houcheng ZhouNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Gangwan Road No.28, Guancheng Region, Zhengzhou, 450009, China. zhouhoucheng@caas.cn.

Funding

The Agricultural Science and Technology Innovation Program CAAS-ASTIP-2025-ZFRIThe Henan Provincial Key Research and Development Program 261111110800The Scientific Research Team of Zhongyuan Research Center, Chinese Academy of Agricultural Sciences CAAS-ZRC-ZYZX20230210
6 · The paper itself

Abstract

backgroundSoluble sugars play a crucial role as a carbon and energy source, with their content and composition governing the flavor profile of fruits. Yet how the contents of glucose, sucrose, and fructose are regulated remains poorly understood.

resultsIn this study, we identified FabHLH130 as a positive regulator in the sucrose metabolism of 'Snow Princess' fruits. We generated FabHLH130 overexpression lines in the octoploid cultivar 'Benihoppe'. Transcriptome analysis reveals higher expression levels of FaSPS1 and FaINV in the sucrose metabolism pathway related to WT. Moreover, the electrophoretic mobility shift and dual-luciferase assays validated that FabHLH130 directly binds to the promoters of FaSPS1 and FaINV, leading to the positive regulation of their expression and enzyme activity. Compared to the WT, the transgenic lines displayed higher total soluble sugar, glucose, sucrose, and fructose contents.

conclusionsOur findings provide insights into the mechanism by which FabHLH130 is associated with sugar accumulation in strawberry fruits and provide a theoretical foundation for understanding soluble sugar metabolism in plants.

Indexed as

Carbohydrate MetabolismFragariaFruitPlant ProteinsGene Expression Regulation, PlantPlants, Genetically ModifiedSucrosePlant ProteinsSucroseFabHLH130Fragaria 🞪 ananassaSucrose metabolismSugar accumulationTranscriptional activity

Identifiers

PMID42902130
PMCPMC13685226

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