ArticleJournal of materials science. Materials in medicine2026
Efficacy and safety of a novel glaucoma drainage tube with a porous outer structure (GDTI-50H) in rabbit eyes.
Article in Journal of materials science. Materials in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
We developed a novel glaucoma drainage tube, designated as GDTI-50H. The outer opening end of the drainage tube is provided with multiple drainage holes, which allows for normal drainage of aqueous humor through the remaining holes when one of the drainage holes becomes blocked. It is potentially enhancing the sustained drainage efficiency. Fourteen New Zealand white rabbits were randomly assigned to receive GDTI-50H implantation in either the right or left eye as the test eye, with the contralateral eye serving as its own control (undergoing sham surgery). Intraocular pressure(IOP) was continuously monitored within 12 weeks postoperatively, combined with slit-lamp microscopy, anterior segment optical coherence tomography (OCT) imaging, Trypan Blue patency test, and histopathological examination. Results showed that IOP in the test group was significantly lower than that in the control group at 12 weeks postoperatively (all differences were statistically significant, p < 0.05). Anterior segment OCT showed that drainage tube was accurately positioned within the anterior chamber angle without displacement or detachment. The Trypan Blue patency test demonstrated that at 12 weeks postoperatively, Trypan Blue dye could still drain from the anterior chamber into the subconjunctival space in the test group. Hematoxylin and Eosin staining images showed no significant inflammatory cell infiltration around drainage tube. This study demonstrated that after implantation of drainage tube into the anterior chamber of rabbit eyes, and it has certain efficacy and safety in controlling IOP.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.