Evidence map›Paper›PMID 42902021›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Thresholds for clinical importance to improve interpretation of the EORTC QLQ-COMU26 communication questionnaire.

Juan Ignacio Arraras, Johannes Giesinger, Yuichiro Kikawa, Omar Shamieh, Iqbal Bahar, Michael Koller, Anne Bredart, Anna Costantini, Eva Greimel, Monika Sztankay and 13 more

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

23 authors.

Juan Ignacio ArrarasMedical Oncology Department, Hospital Universitario de Navarra, Navarra Institute for Health Research (IdiSNA), Irunlarrea 3, Pamplona, 31008, Spain. jiarraras@correo.cop.es.ORCID http://orcid.org/0000-0002-4415-2570
Johannes GiesingerUniversity Hospital of Psychiatry II, Medical University of Innsbruck, Innsbruck, Austria.
Yuichiro KikawaKansai Medical University Medical Center, Osaka, Japan.
Omar ShamiehDepartment of Palliative Medicine, King Hussein Cancer Center, Amman, Jordan.ORCID http://orcid.org/0000-0002-3635-8624
Iqbal BaharCachar Cancer Hospital and Research Centre, Silchar, India.
Michael KollerCentre for Clinical Studies, University Hospital Regensburg, Regensburg, Germany.
Anne BredartPsycho-Oncology Unit, SHARE - SHs And Outcome Research Team, Institut Curie and City University, Paris, France.
Anna CostantiniPsicologia Clinica e Psico-Oncologia, Clinica Villa Margherita, Rome, Italy.
Eva GreimelMedical University Graz, Graz, Austria.
Monika SztankayUniversity Hospital of Psychiatry II, Medical University of Innsbruck, Innsbruck, Austria.
Lisa M WintnerUniversity Hospital of Psychiatry II, Medical University of Innsbruck, Innsbruck, Austria.
Marina Carreiro de SousaUniversidade dos Açores, Ponta Delgada, Portugal.
Hiroto IshikiNational Cancer Center Hospital, Tokyo, Japan.ORCID http://orcid.org/0000-0002-0800-2161
Meropi KontogianniDepartment of Nutrition and Dietetics, Harokopio University of Athens, Kallithea, Greece.
Maja WolanUniversity of Rzeszow, Rzeszów, Poland.
Anne LanceleyDept of Women's Cancer, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London, London, UK.
Ioannis GioulbasanisDepartment of Medical Oncology, Animus Kyanus Stavros General Clinic, Larissa, Greece.
Amelie HarleUniversity Hospitals Dorset, Poole, UK.
Angels PontHealth Services Research Group, IMIM (Hospital del Mar Medical Research Institute), CIBER in Epidemiology and Public Health, CIBERESP, Barcelona, Spain.ORCID http://orcid.org/0000-0002-0602-552X
Jose Juan IllarramendiMedical Oncology Department, Hospital Universitario de Navarra, Navarra Institute for Health Research (IdiSNA), Irunlarrea 3, Pamplona, 31008, Spain.
Tihana GašpertFaculty of Health Sciences, University of Maribor, Maribor, Slovenia.ORCID http://orcid.org/0000-0002-0983-1551
Dirk HofmeisterDepartment of Medical Psychology and Medical Sociology, University of Leipzig, Leipzig, Germany.
Karin KuljanicUniversity Hospital Center Rijeka, Rijeka, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study defined thresholds for clinical importance (TCIs) for the European Organisation for Research and Treatment of Cancer Communication Questionnaire (EORTC QLQ-COMU26). TCIs support the clinical evaluation of individual patients' communication with professionals.

methodsIn this cross-sectional study, an international sample of cancer patients with mixed diagnoses and treatments completed the EORTC QLQ-COMU26, which comprises six scales and four individual items. Item 26, which evaluates patients' satisfaction with communication with professionals, served as the anchor for detecting a negative event (unsatisfactory communication). Diagnostic accuracy for each domain was determined using ROC analysis, and the sensitivity of the TCIs was evaluated. Sensitivity analyses using multivariate binary logistic regression explored potential variability in TCIs across patient groups.

resultsA total of 988 patients from 13 countries participated (mean age, 60.7; 50.0% female). TCIs ranged from 80.3 to 92.5 on the 0-100 metric of the QLQ-COMU26 scales. All TCIs demonstrated sensitivity of at least 0.75, and ROC AUC values ranged from 0.80 to 0.90. Separate TCIs were identified for communication with nurses and doctors, with thresholds > 4 points higher for nurses in five QLQ-COMU26 domains. No evidence supported separate thresholds by age, gender, or treatment intention.

conclusionThis study established TCIs with high diagnostic accuracy for the EORTC QLQ-COMU26, supporting its use in clinical practice and research. The findings suggest that the questionnaire can identify patients who report low communication for specific domains and help improve communication in clinical settings.

Indexed as

CommunicationNeoplasmsPatient SatisfactionProfessional-Patient RelationsAdultAgedAged, 80 and overClinical RelevanceCross-Sectional StudiesFemaleHumansLogistic ModelsMaleMiddle AgedROC CurveSensitivity and SpecificityCancerClinical importanceCommunicationEORTC QLQ-COMU26Patient-reported experience measuresThresholds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.