Evidence map›Paper›PMID 42900674›Full record

ArticleCartilage2026

Real-World Evaluation of Repeated Intra-articular 1.0% Sodium Hyaluronate Injections for Knee Osteoarthritis: A 30-Week Post-market Clinical Performance Study.

Tsu-Te Yeh, Ching-Ting Chen, Yung-Hsiang Lin, Chi-Fu Chiang, Yi-Wen Mao

Abstract read
In one paragraph

Article in Cartilage, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tsu-Te YehDepartment of Orthopaedic Surgery, Tri-Service General Hospital, School of Medicine, National Defense Medical University, Taipei, Taiwan.
Ching-Ting ChenMaxigen Biotech Inc., Taoyuan, Taiwan.
Yung-Hsiang LinMaxigen Biotech Inc., Taoyuan, Taiwan.
Chi-Fu ChiangResearch & Design Center, TCI Co., Ltd., Taipei, Taiwan.
Yi-Wen MaoResearch & Design Center, TCI Co., Ltd., Taipei, Taiwan.ORCID 0000-0002-6729-9946

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveTo evaluate the safety and clinical performance of a high-purity, non-cross-linked 1.0% sodium hyaluronate administered via intra-articular injection in patients with symptomatic knee osteoarthritis (OA).DesignThis 30-week, single-center, open-label post-market clinical performance evaluation enrolled adults with radiographically confirmed knee OA. Participants received five weekly intra-articular injections of 1.0% sodium hyaluronate. Resting pain (VAS), Kellgren-Lawrence (KL) grade, and patient satisfaction were assessed through Week 30, and adverse events were monitored throughout.ResultsMean VAS pain scores decreased by 48.3% at Week 8 and 42.8% at Week 30 compared with baseline (both

Indexed as

intra-articular injectionknee osteoarthritisnon–cross-linked sodium hyaluronatepost-market clinical performance evaluationreal-world evidenceviscosupplementation

Identifiers

PMID42900674
PMCPMC13683830

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.