Evidence map›Paper›PMID 42900404›Full record

ArticleJournal of plant research2026

Seasonal variation in the content of β-asarone and related phenylpropenes and their associated transcriptomic profiles in Acorus calamus.

Oyundari Ganbat, Nagomi Kashimoto, Moe Matsumoto, Takumi Ogawa, Takao Koeduka, Bolortuya Ulziibat, Atsushi Okazawa

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Article in Journal of plant research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Oyundari GanbatGraduate School of Agriculture, Osaka Metropolitan University, 1-1 Gakuen-cho, Naka-ku, Sakai, 599-8531, Osaka, Japan.ORCID http://orcid.org/0000-0003-0808-6470
Nagomi KashimotoGraduate School of Agriculture, Osaka Metropolitan University, 1-1 Gakuen-cho, Naka-ku, Sakai, 599-8531, Osaka, Japan.
Moe MatsumotoGraduate School of Agriculture, Osaka Metropolitan University, 1-1 Gakuen-cho, Naka-ku, Sakai, 599-8531, Osaka, Japan.
Takumi OgawaGraduate School of Agriculture, Osaka Metropolitan University, 1-1 Gakuen-cho, Naka-ku, Sakai, 599-8531, Osaka, Japan.ORCID http://orcid.org/0000-0001-6029-0976
Takao KoedukaGraduate School of Science and Technology for Innovation, Yamaguchi University, 1677-1 Yoshida, Yamaguchi, 753-8515, Yamaguchi, Japan.ORCID http://orcid.org/0000-0002-0786-3242
Bolortuya UlziibatDepartment of Research and R&D Policy, Mongolian Academy of Sciences, Enkhtaivan Avenue 54b, Bayanzurkh District, 13330, Ulaanbaatar, Mongolia.ORCID http://orcid.org/0000-0002-7394-4833
Atsushi OkazawaGraduate School of Agriculture, Osaka Metropolitan University, 1-1 Gakuen-cho, Naka-ku, Sakai, 599-8531, Osaka, Japan. okazawa.atsushi@omu.ac.jp.ORCID http://orcid.org/0000-0002-3871-5779

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acorus calamus L. is a monocotyledonous medicinal plant possessing bioactive compounds, including β-asarone, which exhibits anti-microbial, neuroprotective, and antioxidant effects. However, the biosynthetic pathway of β-asarone in A. calamus remains poorly understood. This study investigated seasonal changes in the accumulation of β-asarone and related phenylpropenes and their associated transcriptome. Leaf, root, and rhizome samples were analyzed by gas chromatography, and leaf samples representing periods with the lowest and highest levels of β-asarone and its related phenylpropene (Z)-methylisoeugenol were selected for comparative transcriptome analysis. Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis revealed distinct gene expression patterns during β-asarone accumulation, including the downregulation of most phenylpropanoid biosynthetic genes and upregulation of the genes encoding 4-coumarate-CoA ligase and caffeoyl-CoA O-methyltransferase. Conversely, these genes exhibited different expression patterns during the periods of high (Z)-methylisoeugenol accumulation. This study suggests that β-asarone biosynthesis involves different pathways from predicted phenylpropene routes and provides insights into the seasonal regulation of specialized phenylpropanoid metabolism in A. calamus.

Indexed as

Acorus calamusAsaroneMethylisoeugenolPhenylpropanoidSeasonal changesTranscriptome

Identifiers

PMID42900404

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.