Evidence map›Paper›PMID 42900262›Full record

ReviewPediatric surgery international2026

The urinary microbiome after paediatric bladder augmentation: a scoping review with comparative insights from adult urinary diversion surgeries.

Jeen Liang Low, Yoke Lin Nyo, Ming Chan, Zong Jie Koh

Abstract readScoping ReviewComparative StudyReview
PubMed Publisher
In one paragraph

Review in Pediatric surgery international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeen Liang LowYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Yoke Lin NyoDepartment of Paediatric Surgery, Khoo Teck Puat - National University Children's Medical Institute, National University Hospital, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore.
Ming ChanDepartment of Nursing, Changi General Hospital, Singapore, Singapore.
Zong Jie KohDepartment of Paediatric Surgery, Khoo Teck Puat - National University Children's Medical Institute, National University Hospital, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore. zong_jie_koh@nuhs.edu.sg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bladder augmentation is a lifelong reconstructive procedure for children with severe lower urinary tract dysfunction, but recurrent urinary tract infection, urolithiasis and mucus-related complications remain incompletely understood. This scoping review mapped evidence on the urinary microbiome after paediatric bladder augmentation and assessed transferable insights from adult bowel-derived urinary diversion. A PRISMA-ScR-guided search of PubMed, Embase and Web of Science identified peer-reviewed studies and conference abstracts published from January 2016 to April 2026 that used culture-independent sequencing. Seven studies were included: two paediatric and five adult, comprising three cross-sectional studies, two reports from one prospective cohort and two case reports. Paediatric studies reported contrasting enteric-dominant and native-bladder-like communities, with no consistent clinical associations. Adult studies more consistently suggested time-dependent restructuring, reservoir-specific microbial patterns and fungal involvement, although associations with urinary tract infection remained inconsistent. The paediatric evidence is insufficient to define microbiome composition, temporal behaviour or clinical significance after augmentation. Adult findings primarily provide a methodological template for future prospective, longitudinal, within-patient paediatric studies incorporating standardised urine and mucosal sampling, bacterial and fungal sequencing, metabolomics and predefined clinical outcomes.

Indexed as

MicrobiotaUrinary BladderUrinary DiversionAdultChildHumansAugmentationPaediatric urologySequencingUrinary microbiome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.