ReviewRSC advances2026
Recent advances in structural modification and biological activities of isoliquiritigenin and liquiritigenin.
Review in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Liquiritigenin and isoliquiritigenin, major bioactive flavonoids from licorice, exhibit promising pharmacological properties. However, their poor solubility, low oral bioavailability and weak metabolic stability limit their clinical application. Various site-specific structural modification strategies have been adopted by researchers to tackle these limitations. Functionalization with Mannich bases, prenyloxy groups, thiosemicarbazone moieties, halogens and glycosyl groups, as well as structural modifications
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