Evidence map›Paper›PMID 42899034›Full record

ArticleThe Journal of innovations in cardiac rhythm management2026

Evaluation and Classification of Atrial Arrhythmias from Signatures in Electrographic Flow Metrics.

Steven Castellano, Melissa H Kong, Joshua D'Arcy, Dmytro Perekrestenko, Kent R Nilsson, John D Hummel

Abstract read
In one paragraph

Article in The Journal of innovations in cardiac rhythm management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Steven CastellanoCortex, Inc., Menlo Park, CA, USA.
Melissa H KongCortex, Inc., Menlo Park, CA, USA.
Joshua D'ArcyDepartment of Computer Science, Northwestern University, Chicago, IL, USA.
Dmytro PerekrestenkoAblacon, Inc., Zurich, Switzerland.
Kent R Nilsson *Department of Cardiac Electrophysiology, Piedmont Heart Institute, Athens, GA, USA.
John D Hummel *Department of Cardiology, Ohio State University Wexner Medical Center, Columbus, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients undergoing atrial fibrillation (AF) ablation, it can be difficult at times to distinguish between AF, micro-re-entrant atrial flutters (AFLs), and focal atrial tachycardias (ATs). Understanding the mechanism of arrhythmogenesis can guide ablation lesion sets. Electrographic flow (EGF) mapping displays global atrial wavefront propagations in near-real time. Patterns of EGF can show both regions of stable flow direction over time and disorganized electrical wavefronts. In so doing, it can differentiate mechanisms of arrhythmogenesis. The objective of this study was to evaluate the EGF patterns and metrics that may be used to successfully differentiate mechanisms of arrhythmogenesis. A total of 2933 recordings from 151 patients who underwent EGF mapping were analyzed to determine metrics that could distinguish between mechanisms of arrhythmogenesis. These EGF-derived metrics include: (1) electrographic flow consistency (EGFC), (2) flow angle variability (FAV), (3) source activity, (4) atrial cycle length, (5) mean R-R correlation, and (6) disorganization score. The disorganization score varied the most between AF and AFL or AT (

Indexed as

Arrhythmiasbasket cathetercardiacelectrographic flow mappingpanoramic mapping

Identifiers

PMID42899034
PMCPMC13679923

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.