Evidence map›Paper›PMID 42898971›Full record

ArticleFrontiers in medicine2026

Pulmonary hypertension optimal screening in interstitial lung disease (PHOS-ILD): a scoring system for the detection of pulmonary hypertension in patients with interstitial lung disease.

Theodoros Karampitsakos, Evan Wasserman, Eleni Stagaki, Abhay Thottassery, Jorden Smith, Huda Asif, Brian Soto, Christian Arce Guzman, Jalen Hammonds, Anna Papasarantou and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Theodoros KarampitsakosDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Ubben Center for Pulmonary Fibrosis Research, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Evan WassermanDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Ubben Center for Pulmonary Fibrosis Research, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Eleni StagakiFirst Department of Pulmonary, Critical Care and Sleep Medicine, Hospital for Thoracic Diseases "SOTIRIA," National and Kapodistrian University of Athens, Athens, Greece.
Abhay ThottasseryDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Ubben Center for Pulmonary Fibrosis Research, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Jorden SmithDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Ubben Center for Pulmonary Fibrosis Research, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Huda AsifDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Ubben Center for Pulmonary Fibrosis Research, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Brian SotoDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Ubben Center for Pulmonary Fibrosis Research, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Christian Arce GuzmanDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Ubben Center for Pulmonary Fibrosis Research, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Jalen HammondsDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Ubben Center for Pulmonary Fibrosis Research, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Anna PapasarantouFirst Department of Pulmonary, Critical Care and Sleep Medicine, Hospital for Thoracic Diseases "SOTIRIA," National and Kapodistrian University of Athens, Athens, Greece.
Agamemnon BakakosFirst Department of Pulmonary, Critical Care and Sleep Medicine, Hospital for Thoracic Diseases "SOTIRIA," National and Kapodistrian University of Athens, Athens, Greece.
Ourania PapaioannouFirst Department of Pulmonary, Critical Care and Sleep Medicine, Hospital for Thoracic Diseases "SOTIRIA," National and Kapodistrian University of Athens, Athens, Greece.
Apostolos MatsioulasFirst Department of Pulmonary, Critical Care and Sleep Medicine, Hospital for Thoracic Diseases "SOTIRIA," National and Kapodistrian University of Athens, Athens, Greece.
Foteini KarakontakiFirst Department of Pulmonary, Critical Care and Sleep Medicine, Hospital for Thoracic Diseases "SOTIRIA," National and Kapodistrian University of Athens, Athens, Greece.
Konstantinos LoverdosFirst Department of Pulmonary, Critical Care and Sleep Medicine, Hospital for Thoracic Diseases "SOTIRIA," National and Kapodistrian University of Athens, Athens, Greece.
Eirini KefalidouFirst Department of Pulmonary, Critical Care and Sleep Medicine, Hospital for Thoracic Diseases "SOTIRIA," National and Kapodistrian University of Athens, Athens, Greece.
Brenda M Juan-GuardelaDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Ubben Center for Pulmonary Fibrosis Research, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Jose D Herazo-MayaDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Ubben Center for Pulmonary Fibrosis Research, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Adriano R TonelliDivision of Pulmonary and Critical Care Medicine, Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, OH, United States.
Debabrata BandyopadhyayDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Ubben Center for Pulmonary Fibrosis Research, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulmonary hypertension (PH) is a common comorbidity of interstitial lung disease (ILD). Timely detection may improve outcomes through implementation of PH specific treatments. Methods: Retrospective, multicenter study aiming to identify features that predict PH in patients with ILD. In the derivation cohort (ILD cohort-University of South Florida), we identified predictors of PH in ILD and created a scoring system using the rounded value of odds ratio for each significant parameter. Correlation with hemodynamic parameters was investigated in the derivation and validation cohort (Idiopathic Pulmonary Fibrosis cohort-Cleveland Clinic). Results: We included 164 patients with ILD that underwent right heart catheterization (RHC) [derivation cohort: Conclusion: This study demonstrates that incorporation of demographic, functional, imaging, and echocardiographic characteristics can optimize the early identification of precapillary PH in patients with ILD, paving the way to structured screening strategies. Timely detection of PH might lead to timely implementation of emerging PH specific treatments in patients with ILDs.

Indexed as

identificationinterstitial lung diseasepulmonary hypertensionscoring systemscreening

Identifiers

PMID42898971
PMCPMC13678507

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.