Evidence map›Paper›PMID 42898899›Full record

ReviewFrontiers in immunology2026

Sialidases and sialylated oligosaccharides in intestinal homeostasis and inflammation.

Ezzuddin Abuhussein, Dhirendra K Singh, Yukihiro Yamaguchi, Chiara Elena Orahovats, Olivia G Cassidy, Koichi Tsuboi, Lei Huang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ezzuddin Abuhussein *Children's Research Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Dhirendra K Singh *Department of Rheumatology and Inflammation Research, University of Gothenburg, Gothenburg, Sweden.
Yukihiro Yamaguchi *Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Chiara Elena OrahovatsDietrich School of Arts & Sciences, University of Pittsburgh, Pittsburgh, PA, United States.
Olivia G CassidyWarren Alpert Medical School of Brown University, Providence, RI, United States.
Koichi TsuboiDepartment of Pediatric Surgery, Juntendo University, Tokyo, Japan.
Lei HuangFaculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the variety of hosts, anatomical locations, and symptoms associated with infection, many bacteria have developed mechanisms that allow them to adhere to the cells via carbohydrates. Some of the most dangerous bacterial pathogens including

Indexed as

HomeostasisInflammationIntestinal MucosaIntestinesN-Acetylneuraminic AcidNeuraminidaseOligosaccharidesAnimalsGastrointestinal MicrobiomeHumansIntestinal Barrier FunctionN-Acetylneuraminic AcidNeuraminidaseOligosaccharidesdisialyllacto-N-tetraose (DSLNT)intestinal inflammationpathogenic bacteriasialidasesialyllactose

Identifiers

PMID42898899
PMCPMC13678381

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.