Evidence map›Paper›PMID 42898885›Full record

ArticleCureus2026

A Conservatively Managed Giant Ascending Aortic Aneurysm Presenting With New Atrial Fibrillation and Heart Failure.

Alyaa Hussein, Mohamed Ali, Diane James, Hamza Hamza, Martin Behounek

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alyaa HusseinCardiology, University Hospitals of Leicester NHS Trust, Leicester, GBR.
Mohamed AliCardiology, University Hospitals of Leicester NHS Trust, Leicester, GBR.
Diane JamesRespiratory Medicine, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, GBR.
Hamza HamzaRespiratory Medicine, University Hospitals of Leicester NHS Trust, Leicester, GBR.
Martin BehounekCardiology, University Hospitals of Leicester NHS Trust, Leicester, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ascending aortic aneurysms bigger than 9 cm are not common these days. Most are found and fixed while they are still much smaller. We report an 88-year-old woman who came into hospital with palpitations, worsening breathlessness on exertion, and swollen ankles. She had a history of high blood pressure, stage 3 kidney disease, and high cholesterol. On examination, her pulse was irregular, she had crackles at the bottom of both lungs, and swelling up to her knees. Her ECG showed atrial fibrillation with a fast heart rate, and her B-type natriuretic peptide (BNP) blood test was very high at 4544 ng/L. She was treated for heart failure caused by the new atrial fibrillation and started on medicine to slow her heart rate and thin her blood. An echo scan, done just to check how well her heart was pumping, picked up something unexpected: the main part of her aorta near the heart was very dilated, there was leaking through the aortic valve, and there was fluid around the heart. A CT scan confirmed a 9.3 cm aneurysm of the ascending aorta, starting at the root, with no tear or bleeding. The heart surgeons felt she was too old and frail, with too many other health problems, to have surgery to fix it. She was treated for decompensated heart failure occurring in the setting of new-onset atrial fibrillation with a rapid ventricular response and was started on rate-control therapy and anticoagulation. We talked to her about whether to keep her on blood thinners even though the aneurysm could not be repaired. She chose to stay on her blood thinner after the risks were explained to her. She went home after five days and was doing better when seen again two months later, and the aneurysm had not grown. This case shows how much a routine echo can find, and how hard the decision about blood thinners can be when there is an aneurysm that cannot be operated on.

Indexed as

aortic regurgitationascending aortic aneurysmatrial fibrillationclinical frailty scaleconservative managementdecompensated heart failuredirect oral anticoagulantgiant aortic aneurysmshared decision-making

Identifiers

PMID42898885
PMCPMC13678326

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.