Evidence map›Paper›PMID 42898859›Full record

ArticlePostepy psychiatrii neurologii2026

Gabriela Zdunek, Remigiusz Recław, Krzysztof Chmielowiec, Aleksandra Suchanecka, Ewelina Grywalska, Jolanta Chmielowiec, Dariusz Larysz, Anna Grzywacz

Abstract read
In one paragraph

Article in Postepy psychiatrii neurologii, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gabriela ZdunekIndependent Laboratory of Behavioral Genetics and Epigenetics, Pomeranian Medical University in Szczecin, Poland.ORCID https://orcid.org/0009-0000-2445-3651
Remigiusz RecławIndependent Laboratory of Behavioral Genetics and Epigenetics, Pomeranian Medical University in Szczecin, Poland.ORCID https://orcid.org/0009-0004-7841-821X
Krzysztof ChmielowiecDepartment of Hygiene and Epidemiology, Collegium Medicum, University of Zielona Góra, Zielona Góra, Poland.ORCID https://orcid.org/0000-0003-4254-5466
Aleksandra SuchaneckaIndependent Laboratory of Behavioral Genetics and Epigenetics, Pomeranian Medical University in Szczecin, Poland.ORCID https://orcid.org/0000-0002-7137-1429
Ewelina GrywalskaDepartment of Experimental Immunology, Medical University of Lublin, Lublin, Poland.ORCID https://orcid.org/0000-0002-0451-4741
Jolanta ChmielowiecDepartment of Nursing, Collegium Medicum, University of Zielona Góra, Zielona Góra, Poland.ORCID https://orcid.org/0000-0003-3285-5313
Dariusz LaryszDepartment of Trauma and Orthopedic Surgery, 109th Military Hospital with Polyclinic, Ministry of National Defence, Szczecin, Poland.ORCID https://orcid.org/0009-0007-4267-2250
Anna GrzywaczIndependent Laboratory of Behavioral Genetics and Epigenetics, Pomeranian Medical University in Szczecin, Poland.ORCID https://orcid.org/0000-0002-2633-520X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The objective of the study was to examine the association between Methods: We examined 213 adult women in total, including 101 with a diagnosis of alcohol use disorder (AUD) and 112 non-addicted controls. All participants completed the NEO Five-Factor Inventory (NEO-FFI) and were genotyped for the Results: Women with AUD scored significantly higher on Neuroticism and Openness to Experience, and lower on Extraversion, Agreeableness, and Conscientiousness compared to controls. A significant interaction between Conclusions: These findings suggest that dopaminergic genetic variation may moderate the expression of personality traits in the context of alcohol dependence. Openness to Experience, typically associated with cognitive flexibility, may represent both a vulnerability and an adaptation mechanism in addiction, depending on genetic background. This study emphasizes the importance of considering gene × personality interactions in female addiction research.

Indexed as

alcohol use disorderCOMT rs4680gene × environment interactionNEO-FFIpersonality traits

Identifiers

PMID42898859
PMCPMC13678373

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.