Evidence map›Paper›PMID 42898780›Full record

ArticleInternational journal of microbiology2026

Genotypic and Phenotypic Characterization of MRSA Colonization and Persistence in Residential Aged Care Facilities in Adelaide, Australia.

Belaynesh T Asrat, Sylvia A Sapula, Naomi L Siderius, Jonathan J Whittall, Anteneh Amsalu, Bradley J Hart, Manish Kumar, Morgyn S Warner, John Turnidge, Henrietta Venter

Abstract read
In one paragraph

Article in International journal of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Belaynesh T AsratSchool of Pharmacy and Biomedical Science College of Health Adelaide University Adelaide South Australia Australia adelaide.edu.au.
Sylvia A SapulaSchool of Pharmacy and Biomedical Science College of Health Adelaide University Adelaide South Australia Australia adelaide.edu.au.ORCID https://orcid.org/0000-0002-5534-9774
Naomi L SideriusSchool of Pharmacy and Biomedical Science College of Health Adelaide University Adelaide South Australia Australia adelaide.edu.au.ORCID https://orcid.org/0000-0002-3265-7942
Jonathan J WhittallSchool of Pharmacy and Biomedical Science College of Health Adelaide University Adelaide South Australia Australia adelaide.edu.au.ORCID https://orcid.org/0000-0002-8598-0727
Anteneh AmsaluSchool of Pharmacy and Biomedical Science College of Health Adelaide University Adelaide South Australia Australia adelaide.edu.au.ORCID https://orcid.org/0000-0001-7919-4546
Bradley J HartSchool of Pharmacy and Biomedical Science College of Health Adelaide University Adelaide South Australia Australia adelaide.edu.au.ORCID https://orcid.org/0000-0001-8110-2460
Manish KumarSchool of Pharmacy and Biomedical Science College of Health Adelaide University Adelaide South Australia Australia adelaide.edu.au.ORCID https://orcid.org/0009-0003-6852-4425
Morgyn S WarnerMicrobiology and Infectious Diseases SA Pathology Adelaide South Australia Australia sapathology.sa.gov.au.ORCID https://orcid.org/0000-0002-4053-1610
John TurnidgeSchool of Biological Sciences College of Science Adelaide University Adelaide South Australia Australia adelaide.edu.au.ORCID https://orcid.org/0000-0003-4240-5578
Henrietta VenterSchool of Pharmacy and Biomedical Science College of Health Adelaide University Adelaide South Australia Australia adelaide.edu.au.ORCID https://orcid.org/0000-0001-5569-7755

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Residential aged care facilities (RACFs) are potential reservoirs for methicillin-resistant Objectives: This study is aimed at assessing MRSA prevalence in RACFs and analyzing antimicrobial resistance mechanisms both phenotypically and genotypically. Methods: A total of 106 participants were recruited: 84 from three RACFs and 22 from retirement villages (as control samples). MRSA was isolated from nasal, wound, and urine samples using selective media. Identification was confirmed via MALDI-TOF MS. Antimicrobial susceptibility testing and MRSA screening were conducted using ISO broth microdilution and EUCAST disc diffusion. Whole-genome sequencing and bioinformatics were used to explore resistance mechanisms and clonal transmission. Results: Nasal carriage of MRSA was 8.2% ( Conclusion: This study highlights persistent colonization with hospital-associated MRSA and potential clonal transmission among residents of aged care facilities despite several courses of antibiotics. The predominance of the epidemic ST22 clone and high rates of multidrug resistance underscore the urgent need for targeted infection control, routine genomic surveillance, and antimicrobial stewardship in long-term care settings to prevent MRSA dissemination.

Indexed as

antimicrobial resistanceclonal disseminationgenotypic–phenotypic comparisonhospital-acquired MRSAMRSA carriagemultidrug resistance

Identifiers

PMID42898780
PMCPMC13678850

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.