ArticleRSC advances2026
NIR-triggered gelatin-based hydrogel for ion-mechanical synergistic antibacterial therapy and infected wound closure.
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
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Abstract
Bacterial infection and impaired wound closure remain the leading causes of refractory cutaneous wound healing disorders, inflicting substantial global morbidity and mortality while exacerbating the crisis of antibacterial resistance. Infected cutaneous wounds present a persistent clinical difficulty, given that bacterial infection and inadequate wound closure exacerbate one another. Here, we constructed a hydrogel platform that integrates antibacterial activity and active wound closure through ion-mechanical coupling. The system combines thermoresponsive, catechol-functionalized network with core-shell nanoparticles consisting of a metal-organic framework shell (MOF) encapsulating a liquid metal core (LM). Under near-infrared (NIR) irradiation, the liquid metal generates heat that triggers network contraction to mechanically close the wound. Simultaneously, sustained release of Zn
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Registered trials
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