Evidence map›Paper›PMID 42898733›Full record

ArticleBeyoglu eye journal2026

Acute Effects of Cigarette Smoking on Corneal Tomographic and Biometric Parameters: A Prospective Controlled Study.

Semih Çakmak, Arzu Karakiraz, Gül Beste Can, Adem Tellioğlu, Nilufer Gözüm

Abstract read
In one paragraph

Article in Beyoglu eye journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Semih ÇakmakDepartment of Ophthalmology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Türkiye.
Arzu KarakirazDepartment of Ophthalmology, Efc Surgical Medical Center, Istanbul, Türkiye.
Gül Beste CanDepartment of Ophthalmology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Türkiye.
Adem TellioğluDepartment of Ophthalmology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Türkiye.
Nilufer GözümDepartment of Ophthalmology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the acute effects of cigarette smoking on corneal tomography and ocular biometry. Methods: This prospective, controlled study included 92 healthy volunteers (46 smokers and 46 non-smokers); only the right eye was analyzed. Baseline ophthalmological examination, corneal tomography and biometry were performed. Participants remained outdoors for 10 minutes under standardized conditions; smokers smoked one cigarette, whereas controls did not. Measurements were then repeated, and within-group changes and between-group differences in change (Δ) were analyzed. Results: Baseline demographic, tomographic, and biometric measurements were similar between groups (all p>0.05). Within the smoking group, significant reductions were observed in corneal thickness at the pupil center, corneal vertex, and thinnest point (p=0.011, p=0.012, and p=0.017, respectively). Within the smoking group, anterior chamber depth also decreased from 3.08±0.44 mm to 2.98±0.52 mm (p=0.034); however, the between-group difference in Δ values was not statistically significant (p=0.068). In contrast, no significant changes were observed in anterior chamber volume, keratometric values, axial length, or emmetropia-targeted intraocular lens power calculated using the Barrett Universal II formula (p>0.05 for all). No significant changes were observed in any of the parameters examined in the control group. In the between-group comparison of Δ values, changes in pupil-center pachymetry and thinnest corneal thickness were significantly different (p=0.002 and p=0.004). Anterior 0-2 mm densitometry decreased in smokers, with a significant between-group difference in Δ (p=0.029). Conclusions: Acute cigarette smoking was associated with measurable alterations in corneal thickness, anterior chamber depth and several corneal densitometry parameters. However, these changes did not significantly affect keratometric values, axial length, or intraocular lens power calculations. Recent cigarette smoking may affect anterior segment measurements, and recent cigarette smoking should be considered when interpreting measurements, especially in situations requiring sensitive corneal assessment.

Indexed as

anterior chamberAnterior Eye Segmentcigarette smokingcorneal pachymetrycorneal topography

Identifiers

PMID42898733
PMCPMC13678156

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.