Evidence map›Paper›PMID 42898625›Full record

ReviewClinical and translational radiation oncology2027

Efficacy and safety of single-fraction stereotactic body radiotherapy (SBRT) for the curative treatment of extracranial primary Tumors: A collaborative systematic review on behalf of the SBRT Focus Group of the European Society for Radiotherapy & Oncology (ESTRO).

Francesco Cuccia, Ciro Franzese, Suraiya Dubash, Valeria Dionisi, Thomas Brunner, Francesco Cellini, Juliane Hörner-Rieber, Thomas Zilli, Bartłomiej Tomasik, Dirk Verellen and 2 more

Abstract readReview
In one paragraph

Review in Clinical and translational radiation oncology, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Francesco CucciaRadiation Oncology, ARNAS Civico Hospital, Palermo, Italy.
Ciro FranzeseDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
Suraiya DubashDepartment of Oncology, Mount Vernon Cancer Centre, Northwood, United Kingdom.
Valeria DionisiDepartment of Medical Oncology, University and Hospital Trust, Verona, Italy.
Thomas BrunnerDepartment of Radiation Oncology, Medical University of Graz, Graz, Austria.
Francesco CelliniDepartment of Radiation Oncology, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Rome, Italy.
Juliane Hörner-RieberDepartment of Radiation Oncology, Düsseldorf University Hospital, Düsseldorf, Germany.
Thomas ZilliRadiation Oncology, Oncology Institute of Southern Switzerland; Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Bartłomiej TomasikDepartment of Oncology and Radiotherapy, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland.
Dirk VerellenDepartment of Radiation Oncology, Iridium Network, Wilrijk, (Antwerp), Belgium.
Stephanie Tanadini-LangDepartment of Radiation Oncology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Marta ScorsettiDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single-fraction stereotactic body radiotherapy (SF-SBRT) represents one of the most advanced frontiers in modern radiation oncology. While ultra-hypofractionation has entered everyday clinical practice in different fields of the oncological care, curative treatments in one session are increasingly attractive for the potential favorable combination of logistic advantages with safety and clinical outcomes. This collaborative systematic review promoted by the ESTRO SBRT Focus Group in participation with members of different disease-site Focus Groups collects the available data in support of SF-SBRT for the curative treatment of the main extracranial primary tumors. The findings highlight that, for specific anatomical sites, SF-SBRT is both safe and effective though the results emphasize the critical importance of careful patient selection and mandatory technological requirements for treatment planning and delivery. This collaborative work provides a comprehensive overview of current evidence and identifies key knowledge gaps for future investigation and upcoming clinical trials.

Indexed as

kidney cancerliver cancerlung cancerpancreatic cancerprostate cancersingle-fractionstereotactic body radiotherapy

Identifiers

PMID42898625
PMCPMC13677997

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.