ArticleGlobal challenges (Hoboken, NJ)2026
Global Warming and Type 2 Diabetes: Sex and Gender as Drivers in a Multidimensional Feedback Loop.
Article in Global challenges (Hoboken, NJ), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Climate change is increasingly recognized as a determinant of metabolic health. Emerging evidence indicates that rising temperatures impair glucose homeostasis-specifically through reduced brown adipose tissue activity and increased insulin resistance-thereby exacerbating type 2 diabetes mellitus (T2DM) risk. Concurrently, food systems drive substantial greenhouse gas emissions (GHGE), with gender-differentiated dietary patterns uniquely influencing both environmental impact and health outcomes. In this perspective, we move beyond well-established separate links to propose an original integrated and systemic conceptual framework. This framework connects gender-related drivers in dietary behaviors, GHGE, global warming, brown adipose tissue dysfunction, and T2DM risk into an integrated multidimensional feedback model, providing a novel basis to generate hypotheses for future mechanistic, epidemiological, and intervention studies, supporting gender-sensitive prevention strategies.
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