ArticleHealth science reports2026
Histopathological Spectrum in FIT-Positive Patients With Abnormal Colonoscopy Findings at a Tertiary Medical Center in Lebanon: A Retrospective Observational Study.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Colorectal cancer is a leading cause of cancer-related morbidity and mortality, and the prognosis significantly depends on the diagnostic stage. Various screening initiatives have been established, among which the fecal immunochemical test (FIT) (FITFIT) which is prominent for its affordability, non-invasive approach, and wide acceptance. This study aimed to describe the spectrum of histopathological findings among patients with positive fecal occult blood test and abnormal colonoscopy findings, and to identify associated risk factors. Methods: This retrospective observational study included 172 adults with documented positive FIT and abnormal colonoscopy findings at Makassed General Hospital from January 2024 to December 2025. Statistical analysis was conducted using SPSS version 25, and associations were assessed using chi-square or Fisher's exact tests, with significance defined as Results: A total of 172 patients were included, with a mean age of 63.88 ± 11.79 years, and 55.2% were female. The most frequently recorded indications for colonoscopy were anemia (39%) and screening (37.2%). Polyps were the most common colonoscopy finding. Histopathological examination demonstrated that neoplastic polyps represented the predominant diagnosis (65.1%), followed by non-neoplastic lesions (24.4%) and malignancy (10.5%). Patients aged 45 years and older demonstrated a higher prevalence of polyps on colonoscopy; however, the difference did not reach statistical significance. No significant association was observed between gender and colonoscopy or histopathological findings. Abdominal pain and diarrhea were both significantly associated with non-neoplastic histopathological lesions. Conclusion: Among patients with positive FIT and abnormal colonoscopy findings, neoplastic polyps rather than malignancy represented the predominant histopathological findings, supporting the clinical utility of FIT in detecting clinically important colorectal lesions at earlier stages. In addition, variability in the histopathology depending on the clinical presentation may contribute to clinical assessment and risk stratification. Larger prospective studies are needed to determine predictors of advanced colorectal histopathology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.