Evidence map›Paper›PMID 42898420›Full record

ArticleCase reports in ophthalmological medicine2026

Disseminated Tuberculosis With Ocular Involvement After 12 Years of Anti-TNF-

Muhammad Ali Muslimani, Alberto Ardizzone, Silvia Rossi, Francesco Siviero, Armanda Leka, Marco Vecchia, Alessandra Ricciardi, Pietro Valsecchi, Raffaele Bruno, Angela Maria Di Matteo

Abstract read
In one paragraph

Article in Case reports in ophthalmological medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Muhammad Ali MuslimaniDepartment of Clinical Surgical Diagnostic and Pediatric Sciences University of Pavia Pavia Italy unipv.eu.ORCID https://orcid.org/0000-0002-0926-5457
Alberto ArdizzoneDivision of Ophthalmology IRCCS S. Matteo Hospital Foundation Pavia Italy.
Silvia RossiDivision of Rheumatology IRCCS S. Matteo Hospital Foundation Pavia Italy.ORCID https://orcid.org/0009-0001-0446-6364
Francesco SivieroDepartment of Clinical Surgical Diagnostic and Pediatric Sciences University of Pavia Pavia Italy unipv.eu.ORCID https://orcid.org/0009-0008-7853-9360
Armanda LekaDepartment of Clinical Surgical Diagnostic and Pediatric Sciences University of Pavia Pavia Italy unipv.eu.ORCID https://orcid.org/0009-0008-8789-4137
Marco VecchiaDivision of Infectious and Tropical Diseases IRCCS S. Matteo Hospital Foundation Pavia Italy.ORCID https://orcid.org/0000-0002-6660-2448
Alessandra RicciardiDivision of Infectious and Tropical Diseases IRCCS S. Matteo Hospital Foundation Pavia Italy.ORCID https://orcid.org/0000-0001-5784-0770
Pietro ValsecchiDivision of Infectious and Tropical Diseases IRCCS S. Matteo Hospital Foundation Pavia Italy.ORCID https://orcid.org/0000-0002-3425-9817
Raffaele BrunoDepartment of Clinical Surgical Diagnostic and Pediatric Sciences University of Pavia Pavia Italy unipv.eu.ORCID https://orcid.org/0000-0002-0235-9207
Angela Maria Di MatteoDivision of Infectious and Tropical Diseases IRCCS S. Matteo Hospital Foundation Pavia Italy.ORCID https://orcid.org/0000-0002-2307-1544

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ocular tuberculosis (TB) is an uncommon yet potentially vision-threatening manifestation of Case Presentation: We describe a 52-year-old woman with rheumatoid arthritis receiving long-term adalimumab and methotrexate who developed disseminated TB with pulmonary, splenic, and ocular involvement after 12 years of anti-TNF- Discussion: This case underscores the persistent long-term risk of TB reactivation during prolonged anti-TNF- Conclusion: TB should remain a diagnostic consideration in patients receiving biologic therapy who develop compatible systemic or ocular manifestations, even after long-term treatment and negative baseline screening. Close multidisciplinary collaboration is essential for the diagnosis and management of ocular TB in this population.

Indexed as

adalimumabanti–TNF-α therapychoroidal granulomadisseminated tuberculosisinfectious diseasesMycobacterium tuberculosisocular tuberculosisophthalmologyrheumatoid arthritisrheumatology

Identifiers

PMID42898420
PMCPMC13678034

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.