ArticleFrontiers in bioengineering and biotechnology2026
Quantitative analysis of posture and gait in the differential diagnosis of functional and organic motor disorders: a multicenter cross-sectional study.
Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
44 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Functional Motor Disorders (FMDs) are characterized by impaired motor control in the absence of identifiable structural abnormalities, making their distinction from Organic Motor Disorders (OMDs) a persistent clinical challenge. Quantitative evaluation of gait and postural control may offer objective markers to characterize motor abnormalities and support the differential diagnosis between functional and organic conditions. This study aimed to characterize gait and postural performance in individuals with FMDs compared to those with OMDs and healthy controls (HCs), using dual-task and sensory manipulation paradigms, and to examine their relationship with psychometric variables. Methods: In this multicenter cross-sectional study, patients with clinically definite FMDs (n = 149), OMDs (n = 99), and HCs (n = 153) underwent standardized assessments of posture and gait under single- and dual-task conditions (both motor and cognitive), as well as with eyes open and closed. Spatiotemporal gait parameters, stabilometric measures, and dual-task effects were analyzed. Psychometric variables were also collected to explore their association with motor performance. Results: Compared to OMDs and HCs, individuals with FMDs exhibited significantly greater postural instability, an opposite response to dual-task conditions, and increased stride time variability (all p < 0.05). In this group, motor performance was significantly associated with anxiety, depression, and fatigue, whereas alexithymia was associated with poorer gait performance only in OMDs and HCs (p < 0.05). Discussion: In conclusion, FMDs display a distinct motor and behavioral profile, particularly in response to dual-task paradigms. Quantitative measures such as dual-task effect, sway area under eyes-closed conditions, and stride time variability (all p < 0.05) may represent promising markers for differentiating functional from organic motor disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.