Evidence map›Paper›PMID 42898362›Full record

ArticleFrontiers in bioengineering and biotechnology2026

RCSB PDB web portal RCSB.org for biotechnology research: exploration and visualization of plastic-degrading enzymes at the atomic level in 3D.

Alison Biester, Christine Zardecki, Yana Rose, Joan Segura, Jose M Duarte, Stephen K Burley

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alison BiesterResearch Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey, New Brunswick, NJ, United States.
Christine ZardeckiResearch Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey, New Brunswick, NJ, United States.
Yana RoseResearch Collaboratory for Structural Bioinformatics Protein Data Bank, San Diego Supercomputer Center, University of California, La Jolla, CA, United States.
Joan SeguraResearch Collaboratory for Structural Bioinformatics Protein Data Bank, San Diego Supercomputer Center, University of California, La Jolla, CA, United States.
Jose M DuarteResearch Collaboratory for Structural Bioinformatics Protein Data Bank, San Diego Supercomputer Center, University of California, La Jolla, CA, United States.
Stephen K BurleyResearch Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey, New Brunswick, NJ, United States.

Funding

PDB Management by the Research Collaboratory for Structural BioinformaticsR01GM157729 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI STEPHEN K BURLEY · 2024 to 2026
$11.6M
NIGMS NIH HHS R01 GM157729
6 · The paper itself

Abstract

Introduction: The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) develops resources for biomolecular structure exploration and analysis that are used by an interdisciplinary community of bio scientists, researchers, and students numbering in the many millions worldwide. The RCSB.org website and suite of APIs provide access to more than 250,000 experimentally determined structures archived in the PDB, making it an invaluable tool for biotechnology, such as research on plastic-degrading enzymes. Engineering plastic-degrading enzymes represents a promising strategy for mitigating environmental accumulation of polyethylene terephthalate (PET). Methods: In recent years, RCSB.org has provided access to more than 1 million Computed Structure Models (CSMs) alongside experimentally determined structures and introduced new tools for 3D Motif Search, Visualizing Sequence Annotations in 3D, and Pairwise Structure Alignment. Results and discussion: To identify site-directed mutagenesis targets for improving PET-degrading enzyme efficiency, biotechnology researchers utilize 3D structure data freely available from the PDB. This article describes how RCSB PDB tools for Advanced Search, Visualizing Sequence Annotations in 3D, and Pairwise Structure Alignment can be used to study plastic-degrading enzyme structure and function.

Indexed as

pairwise structure alignmentplastic-degrading enzymesprotein data bankprotein structuresequence annotations in 3Dstructural analysisstructure search

Identifiers

PMID42898362
PMCPMC13677904

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.