ArticleFrontiers in pediatrics2026
A multicenter study on the profile of fungal infections in children infected with HIV in tertiary hospitals in South Western Nigeria.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Fungal infections in children infected with human immunodeficiency virus (HIV) are a significant cause of morbidity and mortality. However, there are no reports on this subject in Nigerian children. Objective: This study aimed to document the spectrum of fungal infections and their outcomes in Nigerian children infected with HIV. Methodology: The case records of all children infected with HIV in three South West Nigerian tertiary hospitals were studied. Data on the identified fungal infection, clinical presentation, and outcomes were obtained and analyzed. Results: A total of 175 children infected with HIV, comprising 89 (50.9%) boys and 86 (49.1%) girls, with ages ranging from 2 months to 16 years, were studied. Of the population studied, 83 (47.4%) had dermatophytosis and 24 (13.7%) had invasive fungal infections (IFIs). Tinea capitis, thrush (pityriasis versicolor), and tinea corporis constituted more than 75% of the dermatophytosis. Invasive candidiasis, Conclusion: Fungal infections cause significant morbidity and mortality in children infected with HIV. Appropriate diagnostics and medications must be made accessible to reverse IFI treatment outcomes.
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