ArticleFrontiers in cellular and infection microbiology2026
Differences in microbiota profiles of simple and complicated pediatric appendicitis cases.
Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This study aimed to identify the differences in microbial composition between simple appendicitis (SA) and complicated appendicitis (CA) in a limited sample size using culture and microbiota analysis. Appendix tissues and rectal swabs for microbiota analysis and conventional cultures were collected from patients. 16S rRNA regions were amplified using a DNA preparation kit with primers designed to target the V3-V4 region. Sixteen (41%) of the patients were classified as CA based on the histopathological analysis, and the rest as SA. The effect size was slightly greater in rectal swab samples than in appendiceal tissue samples. Based on the conventional culture, the most common aerobic bacteria were
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