Evidence map›Paper›PMID 42898109›Full record

ArticleiScience2026

Reconstructing the genetic ancestry of the archaeological site in Amiternum: From Roman Imperial to early medieval times in Central Italy.

Elisabetta Moroni, Vincenzo Agostini, Dario Ciabini, Giulia Colombo, Rosalinda Di Gerlando, Nicola Rambaldi Migliore, Osvaldo Zarivi, Ornella Semino, Alessandro Achilli, Alfonso Forgione and 2 more

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Elisabetta MoroniDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, via Ferrata 9, 27100 Pavia, Italy.
Vincenzo AgostiniDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, via Ferrata 9, 27100 Pavia, Italy.
Dario CiabiniDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, via Ferrata 9, 27100 Pavia, Italy.
Giulia ColomboDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, via Ferrata 9, 27100 Pavia, Italy.
Rosalinda Di GerlandoMolecular Biology and Transcriptomic Unit, IRCCS Mondino Foundation, via Mondino 2, 27100 Pavia, Italy.
Nicola Rambaldi MiglioreDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, via Ferrata 9, 27100 Pavia, Italy.
Osvaldo ZariviDepartment of Clinical Medicine, Public Health, Life and Environmental Sciences, University of L'Aquila, piazzale Salvatore Tommasi 1, 67100 L'Aquila, Italy.
Ornella SeminoDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, via Ferrata 9, 27100 Pavia, Italy.
Alessandro AchilliDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, via Ferrata 9, 27100 Pavia, Italy.
Alfonso ForgioneDepartment of Human Studies, University of L'Aquila, viale Nizza 14, L'Aquila, Italy.
Anna Maria G PomaDepartment of Clinical Medicine, Public Health, Life and Environmental Sciences, University of L'Aquila, piazzale Salvatore Tommasi 1, 67100 L'Aquila, Italy.
Anna OlivieriDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, via Ferrata 9, 27100 Pavia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central-southern Italy is pivotal for reconstructing the population history of the peninsula, yet the genetic impact of the complex demographic past in the Abruzzo region remains largely unexplored. This study integrates archaeological context with ancient DNA analysis of 16 individuals excavated at the Cathedral of Santa Maria in Civitate in Amiternum. The sample comprises one adult male from the Roman Imperial period and 15 subadults mainly from the early medieval period. Genome-wide data reveal a sharp genetic discontinuity between the two epochs. The Roman individual mirrors other Italians from the same period, characterized by significant Near Eastern ancestry. In contrast, the early medieval group-genetically homogeneous-clusters with late antique and medieval populations from Central and Southern Italy, showing significant genetic influence from Central and Northern Europe. Overall, the medieval genetic structure differs from the Roman one and closely resembles that of modern Central and Southern Italians.

Indexed as

ancient DNAancient ItalyarchaeogenomicsMiddle AgesRoman Empire

Identifiers

PMID42898109
PMCPMC13677311

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.