Evidence map›Paper›PMID 42898103›Full record

ArticleiScience2026

The circulating lipidome in severe obesity.

Mohammad Yaser Anwar, Heather M Highland, Alexandra B Palmer, Thy Duong, Zhaotong Lin, Wanying Zhu, Jessica Sprinkles, Daeeun Kim, Kristin L Young, Hung-Hsin Chen and 17 more

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Mohammad Yaser AnwarDepartment of Epidemiology, The University of Texas Health Science Center at Houston School of Public Health, Houston, TX 77030, USA.
Heather M HighlandDepartment of Epidemiology, The University of Texas Health Science Center at Houston School of Public Health, Houston, TX 77030, USA.
Alexandra B PalmerDepartment of Epidemiology, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27517, USA.
Thy DuongBaker Heart and Diabetes Institute, Melbourne, VIC 3004, Australia.
Zhaotong LinDepartment of Statistics, Florida State University, Tallahassee, FL 32306, USA.
Wanying ZhuDepartment of Medicine, Division of Genetic Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Jessica SprinklesDepartment of Nutrition, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27517, USA.
Daeeun KimDepartment of Epidemiology, The University of Texas Health Science Center at Houston School of Public Health, Houston, TX 77030, USA.
Kristin L YoungDepartment of Epidemiology, The University of Texas Health Science Center at Houston School of Public Health, Houston, TX 77030, USA.
Hung-Hsin ChenAcademia Sinica, Institute of Biomedical Sciences, Taipei 115, Taiwan.
Mohanraj KrishnanDepartment of Biobehavioral Health, Pennsylvania State University, University Park, PA 16802, USA.
Absalon GutierrezDepartment of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, The University of Texas Health Science Center, Houston, TX 77030, USA.
Rashedeh RoshaniDepartment of Medicine, Division of Genetic Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Elizabeth G FrankelDepartment of Medicine, Division of Genetic Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Joshua LandmanDepartment of Medicine, Division of Genetic Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Penny Gordon-LarsenDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27517, USA.
Susan K FriedDiabetes, Obesity Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Miryoung LeeDepartment of Epidemiology, The University of Texas Health Science Center at Houston School of Public Health, Houston, TX 77030, USA.
Susan P Fisher-HochDepartment of Epidemiology, The University of Texas Health Science Center at Houston School of Public Health, Houston, TX 77030, USA.
Joseph B McCormickDepartment of Epidemiology, The University of Texas Health Science Center at Houston School of Public Health, Houston, TX 77030, USA.
Joanne CurranDepartment of Human Genetics and South Texas Diabetes and Obesity Institute, School of Medicine, University of Texas of the Rio Grande Valley, Brownsville, TX 78520, USA.
John BlangeroDepartment of Human Genetics and South Texas Diabetes and Obesity Institute, School of Medicine, University of Texas of the Rio Grande Valley, Brownsville, TX 78520, USA.
Peter J MeikleBaker Heart and Diabetes Institute, Melbourne, VIC 3004, Australia.
Corey GilesBaker Heart and Diabetes Institute, Melbourne, VIC 3004, Australia.
Jennifer E BelowVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Kari E NorthDepartment of Epidemiology, The University of Texas Health Science Center at Houston School of Public Health, Houston, TX 77030, USA.
Mariaelisa GraffDepartment of Epidemiology, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27517, USA.

Funding

Center for Clinical and Translational Sciences (CCTS)UL1TR000371 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$13.4M
Polygenic Risk Scores for Diverse Populations - Bridging Research and Clinical CareR01HL151152 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Christy Leigh Avery, Jennifer Below · 2020 to 2026
$12.3M
Leveraging multi-omics approaches to examine metabolic challenges of obesity in relation to cardiovascular diseasesR01HL143885 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI AVERY, CHRISTY LEIGH, GORDON-LARSEN, PENNY · 2019 to 2022
$8.9M
PAGE III: Population Architecture using Genomics and EpidemiologyR01HG010297 · NHGRI · RUTGERS, THE STATE UNIV OF N.J. · PI GIGNOUX, CHRISTOPHER R, MATISE, TARA C. · 2019 to 2022
$6.5M
Gene-Environment Interactions and Weight GainR01HD057194 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GORDON-LARSEN, PENNY, NORTH, KARI E. · 2008 to 2019
$5.9M
Hispanic Latino Lipid ConsortiumR01HL142302 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jennifer Below, JOSEPH MCCORMICK · 2018 to 2026
$5.8M
Integrative Approaches to Identifying Function and Clinical Significance of Adiposity Susceptibility GenesR01DK122503 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Anne Justice, Ching-Ti Liu · 2020 to 2026
$4.5M
Pharmacogenetics of the Response to GLP-1 in Mexican-Americans with PrediabetesR01DK127084 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI GUTIERREZ, ABSALON DENNIS · 2021 to 2025
$3.5M
Multi-omics for obesity-associated liver disease in a high-risk population cohortU01CA288325 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Jennifer Below, JOSEPH MCCORMICK · 2023 to 2026
$3.3M
Genomic, transcriptomic, and metabolic effects on skeletal health in Mexican AmericansR01AG078452 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MIRYOUNG LEE, Nahid J. Rianon · 2023 to 2026
$2.7M
Genetic Determinants of Lipidomic Variation and Their Role in CVD RiskR01HL140681 · NHLBI · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI CURRAN, JOANNE E., MEIKLE, PETER JOHN · 2018 to 2021
$2.4M
NCATS NIH HHS UL1 TR000371NCI NIH HHS U01 CA288325NHGRI NIH HHS R01 HG010297NHLBI NIH HHS R01 HL140681NHLBI NIH HHS R01 HL142302NHLBI NIH HHS R01 HL143885NHLBI NIH HHS R01 HL151152NIA NIH HHS R01 AG078452NICHD NIH HHS R01 HD057194NIDDK NIH HHS R01 DK122503NIDDK NIH HHS R01 DK127084
6 · The paper itself

Abstract

Severe obesity (SevO; BMI ≥ 40 kg/m

Indexed as

cardiometabolic disordersMexican American populationplasma lipid speciessevere obesity

Identifiers

PMID42898103
PMCPMC13677329

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.