Evidence map›Paper›PMID 42897966›Full record

SynthesisJournal of the International Society of Sports Nutrition2026

Placebo effects of caffeine on sport performance: a systematic review and meta-analysis.

Philip Hurst, Janina Hanssen, Felipe Marticorena, Lieke Schiphof-Godart, Hiago L R Souza, Moacir Marocolo, Bryan Saunders

Abstract readSystematic ReviewMeta-AnalysisReview
In one paragraph

Synthesis in Journal of the International Society of Sports Nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Placebo effects of caffeine on sport performance: a systematic review and meta-analysis.Journal of the International Society of Sports Nutrition · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Philip HurstDepartment of Sport & Exercise, Canterbury Christ Church University, Canterbury, United Kingdom.ORCID 0000-0002-9265-2975
Janina HanssenDepartment of Sport & Exercise, Canterbury Christ Church University, Canterbury, United Kingdom.ORCID 0009-0008-2782-6909
Felipe MarticorenaApplied Physiology and Nutrition Research Group - School of Physical Education and Sport and Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0002-8712-4975
Lieke Schiphof-GodartErasmus University Rotterdam, Department of Medical Informatics, Rotterdam, The Netherlands.ORCID 0000-0001-9190-5398
Hiago L R SouzaPostgraduate Program in Biosciences and Human Health, Minas Gerais State University, Divinopolis, Minas Gerais, Brazil.ORCID 0000-0002-2488-7502
Moacir MarocoloFederal University of Juiz de Fora, Department of Physiology, Juiz de Fora, Sao Paulo, Brazil.ORCID 0000-0002-7715-2534
Bryan SaundersApplied Physiology and Nutrition Research Group - School of Physical Education and Sport and Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0003-0995-9077

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA body of research has shown that deceptively administering a placebo described as caffeine can significantly improve sport performance. We aimed to synthesize and estimate the effect size of the deceptive administration of a placebo described as caffeine on sport performance outcomes (e.g. bench press, cycling time-trial, repeated sprint).

methodsWe searched for studies sampling healthy adults from database creation to July 2026. The standardized mean difference (

resultsSeventeen studies were included. Nine studies were judged to be of high-risk of bias and eight unclear. Random-effect models revealed a small-to-moderate effect of placebo caffeine benefiting performance ( DISCUSSION: Data highlight that placebo effects of caffeine can significantly affect sport performance with a pooled effect estimate suggesting a small-to-moderate effect. However, as per the GRADE assessment, the overall quality of evidence was low. As such, given the high risk of bias across all studies and the variation in confidence interval, stronger research designs are needed to examine placebo effects of caffeine, whereby researchers are blinded to treatment administration and allocation concealment. No funding was received for the review and the protocol can be found here: doi: 10.17605/OSF.IO/W8KY6.

Indexed as

Athletic PerformanceCaffeinePerformance-Enhancing SubstancesPlacebo EffectHumansCaffeinePerformance-Enhancing SubstancesCoffeedietary supplementsexercisemotor controlpsychobiology

Identifiers

PMID42897966
PMCPMC13686187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.