ArticlePhysiological reports2026
Exercise training does not mitigate high-phosphate diet-induced mitochondrial dysfunction in skeletal muscle in male mice.
Hannah F Sanders, Dominic W Kolonay, Jade A Blackwell, Jiaru Liu, Isabella R Dobrski, Daniel A Branch, Lucas A Lefers, Benjamen H Kern, Kedryn K Baskin
Abstract read
In one paragraphArticle in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
9 authors.
Hannah F SandersDepartment of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA.
Dominic W KolonayDepartment of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA.
Jade A BlackwellDepartment of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA.
Jiaru LiuDepartment of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA.
Isabella R DobrskiDepartment of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA.
Daniel A BranchDepartment of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA.
Lucas A LefersDepartment of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA.
Benjamen H KernDepartment of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA.
Funding
Training To Provide the Knowledge, Skills, and Culture To the Next Generation of Cardiovascular ScientistsT32HL134616 · NHLBI · OHIO STATE UNIVERSITY · PI Brandon J Biesiadecki, Jill A Rafael-Fortney · 2017 to 2026
$2.6MTranscriptional Coordination and Gene Regulation by MED12 in the CardiomyocyteR01HL166520 · NHLBI · OHIO STATE UNIVERSITY · PI KEDRYN K BASKIN · 2023 to 2026
$2.3MCellular, molecular, and biochemical sciences training grantT32GM141955 · NIGMS · OHIO STATE UNIVERSITY · PI Jane Elizabeth Jackman, JESSE J KWIEK · 2021 to 2026
$2.2MCardiomyokines regulate inter-organ communication and metabolismK01DK116916 · NIDDK · OHIO STATE UNIVERSITY · PI BASKIN, KEDRYN K · 2018 to 2021
$428kHHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL166520HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) T32HL134616HHS | NIH | National Institute of General Medical Sciences (NIGMS) T32GM141955HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases (DEM) K01DK116916NHLBI NIH HHS R01 HL166520NHLBI NIH HHS T32 HL134616NIDDK NIH HHS K01 DK116916NIGMS NIH HHS T32 GM141955
6 · The paper itselfAbstract
Inorganic phosphate consumption in adults is two-to-three-fold higher than the recommended daily allowance due to its widespread use as a preservative and flavor enhancer in processed foods. We previously reported that 12 weeks of high-phosphate diet (HPD) reduced VO
Indexed as
DietMitochondria, MuscleMuscle, SkeletalPhosphatesPhysical Conditioning, AnimalAnimalsMaleMiceMice, Inbred C57BLOxygen ConsumptionPhosphatesexercisehigh‐phosphate dietmitochondrial respirationskeletal muscle metabolism
Identifiers
PMID42897930
PMCPMC13680854
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