Evidence map›Paper›PMID 42897893›Full record

ReviewAnti-cancer agents in medicinal chemistry2026

Advances in Chemotherapeutic Potential of Glycoconjugates against Cancer.

Rajnish Kumar, Archna Singh, Avijit Mazumder, Salahuddin, Nardev Singh

Abstract readReview
PubMed Publisher
In one paragraph

Review in Anti-cancer agents in medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rajnish KumarDepartment of Pharmaceutical Chemistry, Noida Institute of Engineering and Technology (Pharmacy Institute), 19, Knowledge Park-II, Greater Noida, 201306, U.P., India.ORCID 0000-0001-7479-696X
Archna SinghDepartment of Pharmacology, Noida Institute of Engineering and Technology (Pharmacy Institute), 19, Knowledge Park-II, Greater Noida, 201306, U.P., India.
Avijit MazumderDepartment of Pharmacology, Noida Institute of Engineering and Technology (Pharmacy Institute), 19, Knowledge Park-II, Greater Noida, 201306, U.P., India.
SalahuddinDepartment of Pharmaceutical Chemistry, Noida Institute of Engineering and Technology (Pharmacy Institute), 19, Knowledge Park-II, Greater Noida, 201306, U.P., India.
Nardev SinghSchool of Pharmacy, Graphic Era Hill University, Dehradun, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing interest in glycoconjugates as potential chemotherapeutic agents against cancer stems from their ability to selectively target biological processes associated with tumor growth and metastasis. Glycoconjugates- compounds in which carbohydrates are covalently linked to proteins, lipids, or other bioactive molecules-have shown considerable promise in enhancing both the efficacy and selectivity of cancer therapies. This review highlights recent advancements in the development of glycoconjugates, focusing on their roles in modulating tumor-associated glycan interactions, improving drug delivery, and overcoming resistance mechanisms. Key breakthroughs include the synthesis of novel glycoconjugate compounds that exhibit enhanced cytotoxicity toward cancer cells while minimizing effects on normal tissues. Additionally, innovative strategies utilizing glycoconjugates as drug carriers or in combination therapies have demonstrated potential in preclinical and clinical studies. These developments suggest that glycoconjugates could play a pivotal role in the future of cancer treatment, offering new avenues for targeted and personalized therapeutic approaches.

Indexed as

Antineoplastic AgentsGlycoconjugatesNeoplasmsAnimalsCell ProliferationDrug Screening Assays, AntitumorHumansMolecular StructureAntineoplastic AgentsGlycoconjugatescancerchemotherapyglycansGlycoconjugateimmunotherapysynthesis

Identifiers

PMID42897893

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.