Rare multi - regional involvement in posterior reversible encephalopathy syndrome with spinal cord involvement of a young hypertensive male: a case report.

Jingjing Dou, Yuxia Li, Xiangzhen Yuan, Hui Zhang

Abstract readCase Reports

In one paragraph

Article in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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4 authors.

Jingjing Dou *Department of Neurology, Weifang people's hospital, Shandong Second Medical University, 151 Guangwen Street, Weifang, Shandong, 261000, China.

Yuxia Li *Department of Neurology, Weifang people's hospital, Shandong Second Medical University, 151 Guangwen Street, Weifang, Shandong, 261000, China.

Xiangzhen YuanDepartment of Neurology, Weifang people's hospital, Shandong Second Medical University, 151 Guangwen Street, Weifang, Shandong, 261000, China.

Hui ZhangDepartment of Neurology, Weifang people's hospital, Shandong Second Medical University, 151 Guangwen Street, Weifang, Shandong, 261000, China. duoduoiq@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPosterior reversible encephalopathy syndrome (PRES) is an acute or subacute cerebral syndrome which primarily manifests as headache, encephalopathy, seizures, and visual disturbances in various combinations. PRES with spinal cord involvement (PRES-SCI) is extremely rare and considered to be a variant of PRES. CASE PRESENTATION: We present a case of PRES-SCI where the patient primarily manifested with bilateral blurred vision. The brain and spinal cord MRI showed that the lesions simultaneously affected the supratentorial region, infratentorial region, and spinal cord, and malignant hypertension was identified as the underlying etiology. After 8 days of blood pressure control, a follow-up MRI revealed obvious disappearance of the imaging lesions and full resolution of the blurred vision.

conclusionsTimely blood pressure management in PRES-SCI, even with extensive cerebral and spinal cord involvement, can lead to rapid symptom resolution and significant lesion reduction on imaging.

Indexed as

HypertensionPosterior Leukoencephalopathy SyndromeSpinal CordAdultBrainHumansMagnetic Resonance ImagingMaleMalignant hypertensionMedulla oblongataPosterior reversible encephalopathy syndrome with spinal cord involvement

Identifiers

PMID42897530

DOI10.1186/s12883-026-05318-1

PMCPMC13681929

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