Evidence map›Paper›PMID 42897481›Full record

ArticleBMC gastroenterology2026

Real world clinical practice patterns in nocturnal GERD management: insights from nationwide RELIEF survey.

Sandip Pal, G Manoharan, Prashant Bhandarkar, P Manohar Reddy, Atul Shende, R S Arun, Balaji Laxminarayana Shetty B, Saptarshi Bishnu, Sanjeeb Roy, Sucheta Mehta and 3 more

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Article in BMC gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Sandip PalSenior Consultant Gastroenterologist and Hepatologist, Narayana Health, Kolkata, India. drsandippall@gmail.com.
G ManoharanConsultant Hepatologist and Gastroenterologist, Gastro Care Clinic, Chennai, India.
Prashant BhandarkarConsultant Gastroenterologist, Gastroenterology and Endoscopy Centre, Dhantoli, Nagpur, India.
P Manohar ReddyConsultant Hepatologist and Gastroenterologist, Asian Institute of Gastroenterology, Hyderabad, India.
Atul ShendeDepartment of Medicine, M.Y. Hospital, Indore, India.
R S ArunSenior Consultant and Head, Institute of Gastroenterology and Liver Diseases, Chennai, India.
Balaji Laxminarayana Shetty BConsultant Gastroenterologist, Manipal Hospital, Bengaluru, India.
Saptarshi BishnuConsultant Hepatologist and Gastroenterologist, Apollo Hospital, Burdwan, West Bengal, India.
Sanjeeb RoyFellow in Advanced GI Endoscopy, Narayana Health, Kolkata, India.
Sucheta MehtaCipla Ltd, Mumbai, India.
Namita GhagCipla Ltd, Mumbai, India.
Apurva JawdekarCipla Ltd, Mumbai, India.
Aniket VaidyaCipla Ltd, Mumbai, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesNocturnal symptoms of GERD interfere with daytime functioning, work, and social activities, thereby negatively affecting health-related quality of life. Therefore, the present survey aimed to evaluate the clinical practice patterns regarding the management of nocturnal GERD in India.

methodsA digital questionnaire-based nationwide RELIEF survey was conducted among health care practitioners (HCPs) with gastroenterology practice across India. Physicians voluntarily responded to the survey questionnaire consisting of 24 questions based on their clinical experience. Following the collection of completed questionnaires, data were reviewed and analyzed.

resultsOf the 500 HCPs who were approached, 498 completed the study. GERD contributed to > 30% of patient burden every month. According to 25.30% of HCPs, 21-30% of patients with GERD complain of nocturnal symptoms. The most common risk factors in patients with nocturnal GERD were late-night meals (67.67%), followed by smoking (51%), BMI > 25 kg/m

conclusionThe survey highlighted key insights into managing nocturnal GERD in India, with nearly one-fourth of GERD patients reporting nocturnal symptoms like heartburn and regurgitation, emphasizing the need for lifestyle modifications and suitable pharmacological interventions. The management strategy primarily includes PPI therapy, with esomeprazole being the preferred choice for nocturnal GERD.

Indexed as

Gastroesophageal RefluxPractice Patterns, Physicians'Proton Pump InhibitorsAdultEsomeprazoleFemaleHumansIndiaMaleMiddle AgedQuality of LifeRisk FactorsSurveys and QuestionnairesEsomeprazoleProton Pump InhibitorsEsomeprazoleHealth-related quality of lifeHeartburnNocturnal GERDProton pump inhibitorsSleep disturbance

Identifiers

PMID42897481
PMCPMC13681958

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.