Evidence map›Paper›PMID 42897468›Full record

ArticleJournal of neurodevelopmental disorders2026

Working memory and language development have a bi-directional longitudinal relationship in autistic preschoolers.

Aanya Sehgal, Gina Schnur, Viviane Valdes, Susan Faja

Abstract read
In one paragraph

Article in Journal of neurodevelopmental disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aanya SehgalDivision of Developmental Medicine, Boston Children's Hospital, Two Brookline Place, BCH3178, Brookline, MA, 02445, USA.
Gina SchnurDivision of Developmental Medicine, Boston Children's Hospital, Two Brookline Place, BCH3178, Brookline, MA, 02445, USA.
Viviane ValdesDivision of Developmental Medicine, Boston Children's Hospital, Two Brookline Place, BCH3178, Brookline, MA, 02445, USA.ORCID http://orcid.org/0000-0001-5809-3877
Susan FajaDivision of Developmental Medicine, Boston Children's Hospital, Two Brookline Place, BCH3178, Brookline, MA, 02445, USA. susan.faja@childrens.harvard.edu.ORCID http://orcid.org/0000-0001-6876-3643

Funding

Charting the trajectory of executive control in autism in order to optimize delivery of interventionR01MH113928 · NIMH · BOSTON CHILDREN'S HOSPITAL · PI FAJA, SUSAN · 2017 to 2021
$2.7M
NIMH NIH HHS R01 MH113928NIMH NIH HHS R01MH113928
6 · The paper itself

Abstract

backgroundAmong neurotypical children working memory and language development are closely related, but the longitudinal relationship between these factors is unknown in autism. This study had the goal of evaluating potential bidirectional relationships between these domains.

methodsA longitudinal design included language and visuospatial working memory assessments across three time points with 160 autistic preschoolers. Time points were one year apart. A cross-lagged panel model (CLPM) using Full-Information Maximum Likelihood (FIML) was used to evaluate longitudinal associations between performance on a working memory task (i.e., the Hide and Seek Task) and language scores (i.e., verbal development quotient).

resultsCross-lagged associations were significant for paths from working memory at the first time point to language at the second time point (β = .31, p = .01) and from language at first time point to working memory at the second time point (β = .40, p < .001). Cross-lagged paths from the second to third time point were not statistically significant in either direction.

conclusionsThis study provides evidence of a bidirectional relationship between working memory and language in autistic toddlers and preschoolers among younger autistic preschoolers. These results highlight working memory as a potential early assessment and intervention domain for improving language outcomes in autism as well as the role of language delays as a factor related to reduced working memory skills later in development.

Indexed as

Autistic DisorderLanguage DevelopmentMemory, Short-TermChild, PreschoolFemaleHumansLongitudinal StudiesMale

Identifiers

PMID42897468
PMCPMC13681962

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.