Evidence map›Paper›PMID 42897420›Full record

ArticleJournal of imaging informatics in medicine2026

BLIX-Ray: Chest X-Ray Report Generation with Vision-Language Models and Reinforcement Learning.

Taymaz Akan, Mohanna Orujpour, Pedram Salehpour, Sergio Alvarado Montalvo, Mohammad A N Bhuiyan

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Article in Journal of imaging informatics in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Taymaz AkanDepartment of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA. taymaz.akan@lsuhs.edu.ORCID http://orcid.org/0000-0003-4070-1058
Mohanna OrujpourDepartment of Computer Engineering, University of Tabriz, Tabriz, Iran.
Pedram SalehpourDepartment of Computer Engineering, University of Tabriz, Tabriz, Iran.
Sergio Alvarado MontalvoDepartment of Radiology and Nuclear Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Mohammad A N BhuiyanDepartment of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA. nobel.bhuiyan@lsuhs.edu.

Funding

Foundation for the National Institutes of Health P20GM121307
6 · The paper itself

Abstract

The radiology report is essential for directing the course of treatment for a patient. However, writing radiology reports is a huge burden for radiologists. Manual reporting faces challenges due to intra-labeler and inter-labeler variability, causing inconsistent patient treatment and diagnostic results, and complicating matters due to alertness and changing judgment. To address these challenges, we propose an automated radiology report generation model tailored for chest X-ray imaging. We introduce BLIX-Ray, a vision-language model (VLM) designed to generate radiology reports using a transfer learning approach. BLIX-Ray fine-tunes the pre-trained BLIP model to extract and align rich visual and textual representations suited to the medical imaging domain. We use reinforcement learning (RL) to directly optimize report generation based on language evaluation metrics in order to further enhance performance. We evaluate BLIX-Ray on two publicly available datasets: IU-Xray and CheXpert Plus. Experimental results demonstrate that our model achieves the highest CIDEr and BERTScore on both datasets, while n-gram-oriented baselines retain an advantage on BLEU. BLIX-Ray integrates reinforcement learning and transfer learning to improve medical report generation under limited and heterogeneous data conditions. The results highlight the potential of vision-language models to support automated and standardized radiology reporting. Notably, BLIX-Ray achieves the best reported CIDEr (0.6534) and BERTScore (0.8765) among the compared methods on IU-Xray and leads on CIDEr, METEOR, and BERTScore on CheXpert Plus (BERTScore 0.8407), demonstrating strong report-level consensus and semantic similarity with the reference reports.

Indexed as

BLIPChest X-rayRadiology report generationReinforcement learning

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.