ArticleInternational journal of behavioral medicine2026
Life's Essential 8 and Psychological Wellbeing in Those with and without Schizophrenia, Schizoaffective Disorder, and Bipolar Disorder.
Article in International journal of behavioral medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPoor cardiovascular health (CVH) remains a leading cause of early mortality among individuals with serious mental illness (SMI). While psychological well-being (PWB) is linked to CVH in the general population, its role among those with SMI is less understood.
methodThis cross-sectional study characterized CVH using the American Heart Association's Life's Essential 8 among those with and without SMI and examined relationships between CVH and PWB. Demographic, clinical, and PWB data were obtained from the electronic health record and a health and wellbeing survey for 156 individuals with SMI and 311 matched controls (2015-2020). CVH and PWB were compared across groups. General linear models examined associations between CVH and PWB factors, and interaction terms tested whether associations differed by SMI status.
resultsIndividuals with SMI had poorer CVH and reported worse PWB in domains of life satisfaction, perceived social support, and gratitude compared to controls. Life satisfaction (b = 1.06, 95% CI [0.35, 1.76], p = 0.004) was positively associated with CVH in the total sample and did not vary by SMI status (p = 0.82). The association of social support with CVH varied by SMI status, such that the positive effect of social support on LE8 was greater among individuals without SMI (b = -11.37, 95% CI [-20.28, -2.48], p = 0.012). Gratitude was not associated with CVH.
conclusionPatients with SMI compared to those without SMI have poorer CVH and PWB. Greater life satisfaction and social support may be protective for CVH, but social support may not have the same association among those with SMI.
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