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ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2026

Circumstances of fall-related fracture events among men in late life.

Kristine E Ensrud, Sheena Patel, Lisa Langsetmo, Peggy M Cawthon, Howard A Fink, John T Schousboe, Deborah Kado, Eric S Orwoll, Osteoporotic Fractures in Men (MrOS) Study

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In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Kristine E EnsrudDivision of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA. ensru001@umn.edu.ORCID http://orcid.org/0000-0002-9069-3036
Sheena PatelCalifornia Pacific Medical Center Research Institute, San Francisco, CA, USA.
Lisa LangsetmoDivision of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
Peggy M CawthonCalifornia Pacific Medical Center Research Institute, San Francisco, CA, USA.
Howard A FinkDepartment of Medicine, University of Minnesota, Minneapolis, MN, USA.
John T SchousboeHealthPartners Institute, Bloomington, MN, USA.
Deborah KadoDepartment of Medicine, Stanford University, Palo Alto, CA, USA.
Eric S OrwollDivision of Endocrinology, Diabetes & Clinical Nutrition, School of Medicine, Oregon Health & Science University, Portland, OR, USA.
Osteoporotic Fractures in Men (MrOS) Study

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
Long term fracture risk and change in peripheral bone in the oldest old men: The MrOS studyR01AG066671 · NIA · CALIFORNIA PACIFIC MED CTR RES INSTITUTE · PI BOUXSEIN, MARY L, CAWTHON, PEGGY MANNEN · 2020 to 2024
$13.3M
Osteoporotic Fractures in Men (MrOS) - San Francisco Coordinating CenterU01AR066160 · NIAMS · CALIFORNIA PACIFIC MED CTR RES INSTITUTE · PI CUMMINGS, STEVEN RON · 2013 to 2017
$9.3M
NCATS NIH HHS UL1 TR002369NIAMS NIH HHS U01 AR066160NIA NIH HHS R01 AG066671
6 · The paper itself

Abstract

Among older men, most fractures occur in late life and are fall-related. We followed 1469 late-life (average age 90 years) men for 3 years to characterize the circumstances of 160 incident fall-related fracture events. Most were due to minimal trauma and occurred indoors when the activity level was normal or less.

introductionOf fractures in older men, most are fall-related and occur in men 80 years and older. To better guide the development of fracture prevention approaches in late-life men, detailed information on fall-related fracture events was collected in a cohort of 1469 active surviving men (mean age 90 years) in the Osteoporotic Fractures in Men study from March 2021 until November 2024.

methodsParticipants were contacted every 4 months to identify fractures confirmed by radiographic report. Fractures are classified as fall- or non-fall-related and characterized by the degree of trauma. Participants further queried about where, when and how fractures occurred.

resultsDuring a mean follow-up of 3 years, there were 169 confirmed clinical fracture events not due to malignancy or severe external trauma; of these, 160 (94.7%) were fall-related. Most fall-related events were due to falls from ≤standing height (88.1%), occurred indoors (70.6%), and when self-reported activity level was ≤normal (82.5%). Regular use of a walking aid was commonly reported (56.3%); however, of the interviews reporting regular use, 42% indicated that the aid was not in use at the time the event occurred. Fall-related events resulted in fractures across multiple skeletal locations; all fracture types most often occurred indoors, except upper limb fractures that most often occurred outdoors (p = 0.001).

conclusionMost clinical fracture events in late-life men are fall-related, due to minimal trauma, occur indoors and when activity level is normal or less. Findings suggest that fracture prevention research in this patient group should prioritize evaluation of interventions that may reduce the risk of indoor falls.

Indexed as

CircumstancesEpidemiologyFallsFracturesOlder men

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.