Evidence map›Paper›PMID 42895886›Full record

ArticleeLife2026

Bruce suppresses autophagy-regulated caspase activity and wing tissue growth in

Natsuki Shinoda, Yutaro Hama, Nozomi Hanawa, Masayuki Miura

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Natsuki ShinodaDepartment of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-6668-8747
Yutaro HamaInstitute for Genetic Medicine, Hokkaido University, Sapporo, Japan.ORCID https://orcid.org/0000-0002-7190-4547
Nozomi HanawaDepartment of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0009-0001-3852-7508
Masayuki MiuraDepartment of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0001-7444-5705

Funding

Japan Agency for Medical Research and Development JP21gm5010001Japan Science and Technology Agency JPMJAX2539Ministry of Education, Culture, Sports, Science and Technology 19K16137Ministry of Education, Culture, Sports, Science and Technology 21H04774Ministry of Education, Culture, Sports, Science and Technology 21K15080Ministry of Education, Culture, Sports, Science and Technology 22H05586Ministry of Education, Culture, Sports, Science and Technology 23H04766Ministry of Education, Culture, Sports, Science and Technology 23K05747Ministry of Education, Culture, Sports, Science and Technology 24H00567Ministry of Education, Culture, Sports, Science and Technology 25H01842
6 · The paper itself

Abstract

Caspases are cysteine-aspartic proteases that mediate both lethal and non-lethal cellular outcomes, including the promotion of tissue growth. However, the mechanisms underlying the differential regulation of these activities remain unclear. We have previously shown that among the two

Indexed as

AutophagyCaspasesDrosophilaDrosophila melanogasterDrosophila ProteinsWings, AnimalAnimalsApoptosisInhibitor of Apoptosis ProteinsProto-Oncogene Proteins c-bcl-2Buffy protein, DrosophilaCaspasesDcp-1 protein, DrosophiladrICE protein, DrosophilaDrosophila ProteinsInhibitor of Apoptosis ProteinsProto-Oncogene Proteins c-bcl-2AlphaFold3apoptosisautophagycaspasecell biologydevelopmental biologyD. melanogastertissue growthTurboID

Identifiers

PMID42895886
PMCPMC13679926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.