Evidence map›Paper›PMID 42895649›Full record

ReviewOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2026

Osteopenia in adolescent idiopathic scoliosis.

Wenjie Zhong, Kai Cao, Fangqian Wu

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In one paragraph

Review in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wenjie ZhongDepartment of Orthopedic Surgery, Affiliated Rehabilitation Hospital of Nanchang University, Nanchang, China.
Kai CaoDepartment of Orthopedic Surgery, Affiliated Rehabilitation Hospital of Nanchang University, Nanchang, China. caokai@ncu.edu.cn.ORCID http://orcid.org/0009-0009-5068-087X
Fangqian WuDepartment of Orthopedic Surgery, Fuzhou First People's Hospital, Fuzhou, China. wuqianfang123@163.com.

Funding

National Key Research and Development Program of China No.2023YFC2507700National Natural Science Foundation of China No.82360419Natural Science Research Project of Guizhou Province No.20252BAC250080
6 · The paper itself

Abstract

backgroundAdolescent idiopathic scoliosis (AIS) is a common type of scoliosis, which occurs in 10 to 18-year-old adolescents and is often accompanied by osteopenia, but the etiology of osteopenia is still unknown. Exploring the etiology may play an important role in fully understanding the pathogenesis of AIS and drawing new treatment ideas. PURPOSE: Understanding the etiology of osteopenia in AIS.

methodsThis article conducted a comprehensive search across PubMed, Web of Science (WOS), and CNKI for literature concerning osteopenia in adolescent idiopathic scoliosis. The primary search strategy employed "(adolescent idiopathic scoliosis) AND (osteopenia)", supplemented by additional keywords encompassing "bone mineralization disorders", "hormones", "leptin", "calcitonin", "vitamin K", "treatment", etc. The review prioritized recent, high-quality literature.

resultsThis review disclosed the research process of osteopenia in AIS and expounded its possible pathogenesis resulting in osteogenic and bone metabolic abnormalities. Meanwhile, this review summarized some other possible pathogenesis, like gut microbiota, nutritional factors resulting in osteopenia in AIS. Furtherly, the article revealed the relationship between osteopenia and AIS treatment outcome.

conclusionsOsteopenia in AIS patients is caused by multiple factors. During the treatment of AIS, it may be necessary to intervene in osteopenia.

Indexed as

Adolescent idiopathic scoliosisBone metabolismEtiologyOsteopeniaPathogenesis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.