Evidence map›Paper›PMID 42895572›Full record

ReviewPediatric nephrology (Berlin, Germany)2026

Therapy for kidney vasculitis in children during the acute phase and maintenance: updates and insights from new adult therapies.

Andrea Angioi, Doloretta Piras, Nicola Lepori, Antonello Pani

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrea AngioiNephrology, Dialysis and Transplantation Unit, "Giuseppe Brotzu" Hospital (ARNAS G. Brotzu), Cagliari, Italy. andrea.angioi@aob.it.ORCID http://orcid.org/0000-0001-8311-5409
Doloretta PirasNephrology, Dialysis and Transplantation Unit, "Giuseppe Brotzu" Hospital (ARNAS G. Brotzu), Cagliari, Italy.
Nicola LeporiDepartment of Medical Science and Public Health, University of Cagliari, Cagliari, Italy.
Antonello PaniDepartment of Medical Science and Public Health, University of Cagliari, Cagliari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kidney vasculitides in children encompass a heterogeneous group of immune-mediated disorders with distinct pathogenic mechanisms but a shared risk of irreversible kidney injury. Although pediatric vasculitides are rare, advances in understanding disease biology, coupled with significant therapeutic developments in adult vasculitides, have reshaped treatment paradigms. This review summarizes current evidence for the acute-phase and maintenance treatment of pediatric kidney vasculitis and examines how emerging adult therapies, including B-cell depletion, complement inhibition, cytokine-directed agents, and treatment de-escalation strategies, may be responsibly adapted for use in children.

Indexed as

ANCA-associated vasculitisIgA vasculitis nephritisKawasaki diseasePediatric vasculitisPolyarteritis nodosaTakayasu arteritis

Identifiers

PMID42895572

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.