Evidence map›Paper›PMID 42895198›Full record

ArticleThe plant genome2026

Comparative genome assemblies reveal distinct allelic and structural variation at blast resistance loci in rice CT21375-F4-4 and Moroberekan.

Federico Martin, Jorge Duitama, Manuel Narvaez, Alvaro L Perez-Quintero, Constanza Quintero, Kamal Neupane, Duvan S Bonilla, Camila Rebolledo Cid, M Fernanda Alvarez, Gloria M Mosquera and 1 more

Abstract readComparative Study
In one paragraph

Article in The plant genome, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Federico MartinDepartment of Agricultural Biology, Colorado State University, Fort Collins, Colorado, USA.ORCID https://orcid.org/0000-0002-7491-4468
Jorge DuitamaSystems and Computing Engineering Department, Universidad de los Andes, Bogotá, Colombia.ORCID https://orcid.org/0000-0002-9105-6266
Manuel NarvaezCIAT, Crops for Nutrition and Health, Cali, Colombia.ORCID https://orcid.org/0000-0002-8061-4365
Alvaro L Perez-QuinteroPlant Health Institute of Montpellier (PHIM), University of Montpellier, CIRAD, INRAE, Institut Agro, IRD, Montpellier, France.ORCID https://orcid.org/0000-0003-3530-8251
Constanza QuinteroCIAT, Crops for Nutrition and Health, Cali, Colombia.ORCID https://orcid.org/0000-0001-5071-9935
Kamal NeupaneDepartment of Agricultural Biology, Colorado State University, Fort Collins, Colorado, USA.ORCID https://orcid.org/0000-0002-8698-2679
Duvan S BonillaSystems and Computing Engineering Department, Universidad de los Andes, Bogotá, Colombia.ORCID https://orcid.org/0009-0002-2686-474X
Camila Rebolledo CidCIRAD, Montpellier, France.ORCID https://orcid.org/0000-0002-4369-5688
M Fernanda AlvarezCIAT, Crops for Nutrition and Health, Cali, Colombia.ORCID https://orcid.org/0000-0003-1104-6306
Gloria M MosqueraCIAT, Crops for Nutrition and Health, Cali, Colombia.ORCID https://orcid.org/0000-0001-6622-7265
Jan E LeachDepartment of Agricultural Biology, Colorado State University, Fort Collins, Colorado, USA.ORCID https://orcid.org/0000-0001-7252-4397

Funding

Foundation for Food and Agriculture Research, "Improving Climate Resilience in Crops" ICRC20-0000000084
6 · The paper itself

Abstract

Rice blast, caused by Magnaporthe oryzae, remains a major constraint to rice (Oryza sativa L.) production, and durable resistance will require broader use of genetic diversity beyond commonly studied elite cultivars. We present chromosome-scale genome assemblies of two agronomically significant but genetically divergent rice cultivars: CT21375-F4-4 (hereafter, CT21) and Moroberekan. Despite their genetic divergence, both cultivars show consistently strong resistance to blast under multiyear field conditions. We combined field phenotyping with genome-wide protein-to-genome alignment, predicted proteome comparisons, nucleotide-binding leucine-rich repeat (NLR) annotation, and locus-specific analyses of cloned blast resistance genes to examine resistance-associated genomic variation in these cultivars. The cultivars contained similar numbers and overall subtype compositions of NLR loci, but differed markedly in their correspondence to characterized blast resistance genes. CT21 contained multiple exact or near-exact matches to cloned blast resistance genes and alleles, whereas Moroberekan contained fewer exact matches and was characterized predominantly by high-identity but divergent homologs, suggesting the presence of divergent alleles or resistance architectures that are not well represented by the cloned gene repertoire. Locus-specific analyses further confirmed that high sequence similarity alone does not reliably predict resistance function, and revealed structural variation, including duplication within the Pish NLR cluster in CT21. These results demonstrate that comparable blast resistance phenotypes can occur in cultivars with distinct allelic and structural architectures at known resistance loci. The assemblies and comparative framework developed here provide resources for identifying resistance diversity that may be overlooked by reference gene or marker-based analyses and for prioritizing candidate loci for functional validation and rice improvement.

Indexed as

Disease ResistanceGenome, PlantOryzaPlant DiseasesAllelesAscomycotaGenetic VariationMagnaporthe

Identifiers

PMID42895198
PMCPMC13678862

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.