Evidence map›Paper›PMID 42894779›Full record

ReviewNAM journal2026

Current knowledge of xenobiotic metabolism in the skin, associated

Nazanin Golbamaki, Sebastien Gregoire, Nicola J Hewitt, Daniela Lange, Ans Punt, Sandrine Spriggs, Sara Sepehri, Nadia Heramvand, Andreea Cuciureanu, Dave Allen and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in NAM journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nazanin GolbamakiL'Oréal, Research & Innovation, Aulnay sous-bois, 93600, France.
Sebastien GregoireSebastien Grégoire Consulting, Thorigny sur Marne, 77400, France.
Nicola J HewittSWS, Erzhausen, 64390, Germany.
Daniela LangeBeiersdorf AG, Hamburg, 22529, Germany.
Ans PuntUnilever Safety, Environmental and Regulatory Science (SERS), Colworth Science Park, Sharnbrook, Bedfordshire, MK44 1LQ, UK.
Sandrine SpriggsUnilever Safety, Environmental and Regulatory Science (SERS), Colworth Science Park, Sharnbrook, Bedfordshire, MK44 1LQ, UK.
Sara SepehriUnilever Safety, Environmental and Regulatory Science (SERS), Colworth Science Park, Sharnbrook, Bedfordshire, MK44 1LQ, UK.
Nadia HeramvandHenkel AG & Co. KGaA, Düsseldorf, 40191, Germany.
Andreea CuciureanuInternational Collaboration on Cosmetics Safety (ICCS), Mount Royal, NJ, 08061, USA.
Dave AllenInternational Collaboration on Cosmetics Safety (ICCS), Mount Royal, NJ, 08061, USA.
Abdulkarim NajjarBeiersdorf AG, Hamburg, 22529, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Next Generation Risk Assessments (NGRAs) of cosmetic ingredients, evaluations of systemic exposure after topical application range from conservative screening estimates to higher tier kinetic models. The latter need robust and predictive

Indexed as

Cosmetic ingredientsIn silico, in vitro and PBK modelsNext generation risk assessmentSkin metabolism

Identifiers

PMID42894779
PMCPMC13677243

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.