Evidence map›Paper›PMID 42894760›Full record

ArticleCureus2026

Undifferentiated Pleomorphic Sarcoma of the Breast: A Case Report and Literature Review.

Mario Della Mura, Filippo Emanuele Angiuli, Erica Ferreri, Vlodymir Munchak, Nicola Porcelli, Alessandro Rizzo, Angela Barile, Giuseppe Broggi, Gabriella Serio, Alda Elena Montanaro and 2 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mario Della MuraSection of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Bari, ITA.
Filippo Emanuele AngiuliSection of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Bari, ITA.
Erica FerreriSection of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Bari, ITA.
Vlodymir MunchakSection of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Bari, ITA.
Nicola PorcelliSection of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Bari, ITA.
Alessandro RizzoS.S.D. C.O.r.O. Bed Management Presa in Carico, TDM, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, ITA.
Angela BarileSection of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Bari, ITA.
Giuseppe BroggiPathology Unit, A.O.U. Policlinico "G. Rodolico - San Marco", University of Catania, Catania, ITA.
Gabriella SerioSection of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Bari, ITA.
Alda Elena MontanaroBreast Unit, Policlinico di Bari, Bari, ITA.
Giuseppe IngravalloSection of Pathology, Department of Emergency and Organ Transplantation, University of Bari "Aldo Moro", Bari, ITA.
Gerardo CazzatoSection of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Bari, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary undifferentiated pleomorphic sarcoma (UPS) of the breast is an extremely rare and highly aggressive soft tissue neoplasm. Representing a diagnosis of exclusion, its rarity and the lack of multicentric studies have prevented the establishment of a clear consensus regarding optimal therapeutic strategies. We report the case of a 68-year-old woman presenting with a 15-cm bleeding right breast mass. Histopathological examination revealed a proliferation of pleomorphic, atypical cells admixed with numerous osteoclast-like giant cells and a high proliferative index (Ki-67 = 95%). Comprehensive molecular profiling identified pathogenic mutations in

Indexed as

breastrare breast malignancysarcoma soft tissueundifferentiated pleomorphic sarcoma (ups)ups

Identifiers

PMID42894760
PMCPMC13676785

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.