Evidence map›Paper›PMID 42894734›Full record

ArticleBioactive materials2027

Injectable mRNA-engineered short fibers deliver temporally coupled mechano-genetic signals to reprogram Schwann cell cytoskeleton for nerve repair.

Jiaying Lin, Shifeng Ling, Xiaoxiao Li, Peipei Liu, Tianqi Wu, Wankun Chen, Xiaotian Zhou, Xuemei Peng, Jionghao Yu, Juan Wang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jiaying LinDepartment of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Perioperative Stress and Protection, 180 Fenglin Road, Shanghai, 200030, PR China.
Shifeng LingDepartment of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, PR China.
Xiaoxiao LiDepartment of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Perioperative Stress and Protection, 180 Fenglin Road, Shanghai, 200030, PR China.
Peipei LiuDepartment of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Perioperative Stress and Protection, 180 Fenglin Road, Shanghai, 200030, PR China.
Tianqi WuDepartment of Radiation Oncology, Huashan Hospital, Fudan University, 958 Jinguang Road, Shanghai, 200025, PR China.
Wankun ChenDepartment of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Perioperative Stress and Protection, 180 Fenglin Road, Shanghai, 200030, PR China.
Xiaotian ZhouDepartment of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Perioperative Stress and Protection, 180 Fenglin Road, Shanghai, 200030, PR China.
Xuemei PengDepartment of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Perioperative Stress and Protection, 180 Fenglin Road, Shanghai, 200030, PR China.
Jionghao YuDepartment of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Perioperative Stress and Protection, 180 Fenglin Road, Shanghai, 200030, PR China.
Juan WangDepartment of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, PR China.
Zhengzhe HuangDepartment of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Perioperative Stress and Protection, 180 Fenglin Road, Shanghai, 200030, PR China.
Yawei DuDepartment of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, PR China.
Qichao WuDepartment of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Perioperative Stress and Protection, 180 Fenglin Road, Shanghai, 200030, PR China.
Changhong MiaoDepartment of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Perioperative Stress and Protection, 180 Fenglin Road, Shanghai, 200030, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Defective Schwann cell (SC) repair programs mediated by cytoskeletal remodeling severely limit functional recovery following peripheral nerve injury (PNI). Here, we report an

Indexed as

Mechanical stimulationmRNA deliveryNerve repairRho GTPaseShort fibers

Identifiers

PMID42894734
PMCPMC13677056

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.