Evidence map›Paper›PMID 42894629›Full record

ArticleiScience2026

Extensive monolayer formation after transplantation depends on an RPE subpopulation derived from human iPSCs.

Karen Tessmer, Juliane Hammer, Sylvia J Gasparini, Klara Schmidtke, Trishla Adhikari, Lea Michalke, Anne Schön, Flavia Sulaj, Liliana R Loureiro, Annika Last and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Karen TessmerCenter for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.
Juliane HammerCenter for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.
Sylvia J GaspariniCenter for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.
Klara SchmidtkeCenter for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.
Trishla AdhikariCenter for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.
Lea MichalkeCenter for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.
Anne SchönCenter for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.
Flavia SulajCenter for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.
Liliana R LoureiroInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Annika LastMiltenyi Biotec B.V. & Co. KG, 51429 Bergisch Gladbach, Germany.
Nadine CheliusMiltenyi Biotec B.V. & Co. KG, 51429 Bergisch Gladbach, Germany.
Annett KurtzMiltenyi Biotec B.V. & Co. KG, 51429 Bergisch Gladbach, Germany.
Hannah JohannsenMiltenyi Biotec B.V. & Co. KG, 51429 Bergisch Gladbach, Germany.
Madalena CaridoCenter for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.
Susanne FergusonCenter for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.
Andreas PetzoldDRESDEN-concept Genome Center, Technology Platform at the Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.
Ulrike A FriedrichDRESDEN-concept Genome Center, Technology Platform at the Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.
Thomas KurthCore Facility Electron Microscopy and Histology, Technology Platform at the Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.
Andreas DahlDRESDEN-concept Genome Center, Technology Platform at the Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.
Anja FeldmannInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Seba AlmedawarCenter for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.
Sebastian KnöbelMiltenyi Biotec B.V. & Co. KG, 51429 Bergisch Gladbach, Germany.
Marius AderCenter for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität Dresden (TUD), 01307 Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loss of retinal pigment epithelium (RPE) in the eye leads to photoreceptor dysfunction, death, and eventually, vision loss. Cell replacement strategies using RPE cells derived

Indexed as

cell surface markermonolayer formationmouse modelretinaretinal pigment epitheliumtransplantation

Identifiers

PMID42894629
PMCPMC13676745

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.