Evidence map›Paper›PMID 42894579›Full record

ArticleiScience2026

Loss of the Asn333 high-mannose

Noriyoshi Manabe, Kazuyoshi Itoh, Shiho Ohno, Ayumi Miura, Aika Miyata, Sora Yashima, Sachiko Komatsu, Tsutomu Fujimura, Hisatoshi Hanamatsu, Jun-Ichi Furukawa and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Noriyoshi ManabeDivision of Structural Glycobiology, Institute of Molecular Biomembrane and Glycobiology, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi 981-8558, Japan.
Kazuyoshi ItohGlycan and Life Systems Integration Center (GaLSIC), Soka University, Hachioji, Tokyo 192-8577, Japan.
Shiho OhnoDivision of Structural Glycobiology, Institute of Molecular Biomembrane and Glycobiology, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi 981-8558, Japan.
Ayumi MiuraDivision of Structural Glycobiology, Institute of Molecular Biomembrane and Glycobiology, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi 981-8558, Japan.
Aika MiyataDivision of Structural Glycobiology, Institute of Molecular Biomembrane and Glycobiology, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi 981-8558, Japan.
Sora YashimaDivision of Structural Glycobiology, Institute of Molecular Biomembrane and Glycobiology, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi 981-8558, Japan.
Sachiko KomatsuDivision of Bioanalytical Chemistry, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi 981-8558, Japan.
Tsutomu FujimuraDivision of Bioanalytical Chemistry, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi 981-8558, Japan.
Hisatoshi HanamatsuInstitute for Glyco-Core Research (iGCORE), Nagoya University, Nagoya 466-8550, Japan.
Jun-Ichi FurukawaInstitute for Glyco-Core Research (iGCORE), Nagoya University, Nagoya 466-8550, Japan.
Kiyohiko AngataGlycan and Life Systems Integration Center (GaLSIC), Soka University, Hachioji, Tokyo 192-8577, Japan.
Akira TogayachiGlycan and Life Systems Integration Center (GaLSIC), Soka University, Hachioji, Tokyo 192-8577, Japan.
Kiyoko F Aoki-KinoshitaGlycan and Life Systems Integration Center (GaLSIC), Soka University, Hachioji, Tokyo 192-8577, Japan.
Yoshihiro AkimotoDepartment of Microscopic Anatomy, Kyorin University School of Medicine, Mitaka, Tokyo 181-8611, Japan.
Tadashi KanameDepartment of Genome Medicine, National Center for Child Health and Development, Tokyo 157-8535, Japan.
Shoko NishiharaGlycan and Life Systems Integration Center (GaLSIC), Soka University, Hachioji, Tokyo 192-8577, Japan.
Yoshiki YamaguchiDivision of Structural Glycobiology, Institute of Molecular Biomembrane and Glycobiology, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi 981-8558, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Missense mutations disrupting

Indexed as

ACP3conformational stabilityglycan-protein interactionsmissense mutationneurodevelopmental diseaseproteostasissite-specific N-glycosylation

Identifiers

PMID42894579
PMCPMC13676724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.