ArticleiScience2026
Comparative efficacy of exercise modalities for mild cognitive impairment in older adults: A network meta-analysis.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
Mild cognitive impairment (MCI) represents a critical window for dementia prevention, yet the comparative efficacy of diverse exercise modalities remains unclear. We conducted a frequentist network meta-analysis of 16 randomized controlled trials to identify the optimal exercise intervention for improving global cognition in older adults with MCI. Combined physical-cognitive training ranked first with a 68.0% probability of being the most effective intervention, followed by Tai Chi (15.9%), while single-mode exercises and control groups showed substantially lower benefits. Interventions requiring simultaneous physical exertion and neural engagement confer superior cognitive benefits. This evidence supports tailored dual-component exercise regimens as a robust non-pharmacological strategy to mitigate cognitive decline in aging populations.
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