Trial reportMolecular nutrition & food research2026
Whole-Food Protein Sources Differentially Modulate Postprandial Plasma Dileucine Profiles in the Post-Exercise State.
Trial report in Molecular nutrition & food research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Dileucine, a leucine-containing dipeptide, may enhance anabolic signaling more than leucine alone. This study examined postprandial plasma dileucine and leucine concentrations after ingesting animal- and plant- whole foods and their association with muscle protein synthesis rates (MPS). Secondary analysis was performed on plasma samples collected from two randomized controlled trials totaling 26 healthy adults (25 ± 4.3 y). Participants consumed low-fat pork (LFP), high-fat ground pork (HFP), complementary rice and beans (COMP), an iso-nitrogenous mixed nutrient beverage (ISO), or a carbohydrate control (CHO). Plasma concentrations and MPS was measured. Plasma dileucine increased significantly only after LFP ingestion (p < 0.05), with a greater 300-min iAUC compared to CHO (p = 0.038). Plasma leucine increased in all conditions except COMP and CHO with LFP demonstrating the highest concentrations (p < 0.05). A modest correlation was observed between dileucine Cmax and the change in MPS (ΔMPS; r = 0.436, p = 0.037), whereas leucine Cmax showed no significant association (r = 0.265, p = 0.102). Whole-food protein sources generally do not elevate plasma dileucine, except for LFP. While dileucine C
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