Evidence map›Paper›PMID 42894174›Full record

ArticleHealth research policy and systems2026

Medical research barriers, facilitators, and motives in a developing country: a mixed-methods single-centre study.

Mohammad Abed, Farhang Rashidi, Mohammad Hassan Bagheri, Alipahsa Meysamie, Milad Shafizadeh

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Article in Health research policy and systems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Mohammad Abed *School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Farhang Rashidi *School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Mohammad Hassan BagheriDepartment of Neurosurgery, Children's Medical Center Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Alipahsa MeysamieDepartment of Preventive and Community Medicine, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Milad ShafizadehDepartment of Neurosurgery, Shariati Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran. Milad_shafizadeh@yahoo.com.

Funding

Tehran University of Medical Sciences and Health Services IR.TUMS.SHARIATI.REC.1404.119
6 · The paper itself

Abstract

backgroundResearch engagement is essential for advancing clinical care and strengthening academic capacity. However, sustained participation is often limited by institutional and workflow constraints. This study assessed perceived research barriers and related factors at Tehran University of Medical Sciences (TUMS) and developed and preliminarily evaluated a context-specific instrument.

methodsA sequential, exploratory, mixed-methods, single-centre study was conducted. Qualitative interviews and focus groups informed the development of a 45-item questionnaire covering 10 domains of research barriers and motives. The final instrument was administered via an online survey, with quota-based stratified sampling across academic roles. Internal consistency was evaluated using Cronbach's alpha.

resultsThe scale showed acceptable internal consistency (α = 0.85), but domain-level reliability was mostly modest (α range: 0.36-0.76), and the a priori 10-domain structure was not confirmed (CFI = 0.69, TLI = 0.66, RMSEA = 0.062, SRMR = 0.17); exploratory analysis supported five to six broader dimensions. A total of 358 participants completed the survey (mean age 28.66 ± 7.38; 62.6% male). The total questionnaire score ranged from 113 to 198, with a mean of 153.66 ± 16.24, indicating moderate-to-strong endorsement of perceived research challenges. The highest domain means were observed for data access and quality (27.01 ± 4.05), financial resources and infrastructure (23.01 ± 4.10), and authorship, ethics, and research performance (17.80 ± 2.95). Total scores did not differ by academic position (P = 0.27), but significant differences were observed in time, workload, and organizational support, as well as in skills, training, and methodological consultation (both P < 0.001). Total scores had a weak but significant correlation with years of research experience (P < 0.001) and H-index (P = 0.01).

conclusionPerceived research barriers at TUMS are broadly endorsed and appear concentrated in modifiable institutional domains, particularly data access and quality, resource constraints, and governance-related factors. Institutional strategies that strengthen data systems, improve access to evidence, and enhance organizational support may improve the feasibility and sustainability of research engagement in similar academic medical settings.

Indexed as

Biomedical ResearchDeveloping CountriesMotivationResearch PersonnelAcademiaAdultFemaleFocus GroupsHumansIranMaleQualitative ResearchReproducibility of ResultsSurveys and QuestionnairesBarrierFacilitatorResearchTehran University of Medical Sciences

Identifiers

PMID42894174
PMCPMC13678940

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.